Turku Centre for Biotechnology is a joint department of the University of Turku and Åbo Akademi University, providing high-end technologies and expertise to academic and industrial researchers. These services benefit from the internationally competitive, excellent research carried out by CBT investigators. Our researchers discover molecular events underlying biological function and identify how this information can be used to improve life quality.
Hot Off the Press
McDonnell LA, Walch A, Stoeckli M, Corthals GL. MSiMass List: A Public Database of Identifications for Protein MALDI MSI. J Proteome Res. 2013 Dec 6. Pubmed
Haikarainen T, Frioux C, Zhnag LQ, Li DC & Papageorgiou AC. Crystal structure and biochemical characterization of a manganese superoxide dismutase from Chaetomium thermophilum. Biochim Biophys Acta. 2013 Dec 3. Pubmed
Dominique Böcking, Oliver Wiltschka, Jenni Niinimäki, Hussein Shokry, Rolf Brenner, Mika Lindén and Cecilia Sahlgren. Mesoporous silica nanoparticle-based substrates for cell directed delivery of Notch signalling modulators to control myoblast differentiation. Nanoscale 2014 Advanced article.
Seyednasrollah F, Laiho A, Elo LL. Comparison of software packages for detecting differential expression in RNA-seq studies. Briefings in Bioinformatics 2013.
Närvä E, Pursiheimo JP, Laiho A, Rahkonen N, Emani MR, Viitala M, Laurila K, Sahla R, Lund R, Lähdesmäki H, Jaakkola P, Lahesmaa R. Continuous Hypoxic Culturing of Human embryonic Stem Cells Enhances SSEA-3 and MYC Levels. PLoS One. 2013 Nov 13;8(11):e78847. Pubmed
Sainio A, Nyman M, Lund R, Vuorikoski S, Boström P, Laato M, Boström PJ, Järveläinen H. Lack of decorin expression by human bladder cancer cells offers new tools in the therapy of urothelial malignancies. PLoS One. 2013 Oct 11;8(10):e76190. Pubmed
A novel feeder-free culture system for human pluripotent stem cell culture and induced pluripotent stem cell derivation. Vuoristo S, Toivonen S, Weltner J, Mikkola M, Ustinov J, Trokovic R, Palgi J, Lund R, Tuuri T, Otonkoski T. PLoS One. 2013 Oct 2;8(10):e76205. Pubmed
Pouwels J, De Franceschi N, Rantakari P, Auvinen K, Karikoski M, Mattila E, Potter C, Sundberg JP, Hogg N, Gahmberg CG, Salmi M, Ivaska J.SHARPIN Regulates Uropod Detachment in Migrating Lymphocytes.Cell Rep. 2013 Nov 5. pii: S2211-1247(13)00580-9. Pubmed
Westermarck J, Ivaska J, Corthals GL. Identification of protein interactions involved in cellular signaling. Mol Cell Proteomics. 2013 Jul;12(7):1752-63. Pubmed
Khanna A, Pimanda JE, Westermarck J. Cancerous Inhibitor of Protein Phosphatase 2A, an Emerging Human Oncoprotein and a Potential Cancer Therapy Target. Cancer Res. 2013 Nov 7. Pubmed
Khanna A, Kauko O, Böckelman C, Schreck I, Szwadja A, Laine A, Partanen J, Pokharel Y, Helenius M, Russel M, Haglund C, Cole K, Klefström J, Aittokallio T, Weiss C, Ristimäki A, Visakorpi T and Westermarck J. Chk1 targeting reactivates PP2A tumor suppressor activity in cancer cells. Cancer Research, Published OnlineFirst September 26, 2013. Pubmed
Jendrossek, D., Hermawan, S., Subedi, B. & Papageorgiou, A.C. Biochemical analysis and structure determination of poly(3-hydroxybutyrate) (PHB) depolymerase PhaZ7 muteins reveal the PHB binding site and details of substrate-enzyme interactions. Mol. Microbiol. 2013 Sep 5 [Epub ahead of print] Pubmed
We offer state-of-the-art technology platforms and expertise in the areas of genomics, proteomics and imaging as well as viral vectors and x-ray crystallography. These core facilities operate within the Biocenter Finland national infrastructure network. Our user base comprises local, national and international scientists. CBT services have contributed significantly to the discovery of creative solutions to biological problems as seen from our publications.
Information on individual services can be found from the above menu. Drop by anytime to learn how CBT can advance your research in ways previously unforeseen!
Minna Kyläniemi, University of Turku, 4th of October, 2013:
Regulation of lymphocyte response in vitro and in vivo
Nelly Rahkonen, University of Turku, 13th of September, 2013:
Regulation of self-renewal and detection of karyotypic changes of pluripotent human embryonic stem cells
Saima Ferraris, Åbo Akademi University, 13th of August, 2013:
Cellular responses to stress and kinase signaling activation : apoptosis and differentiation
Soile Tuomela, University of Turku, 26th of April, 2013:
System-level characterization of Th2 cell development and immune
cell responses to ZnO and TiO2 nanoparticles.
Mari Björkman, University of Turku, 1st of March, 2013:
Identification of Epigenetic Targets in Prostate Cancer for
Artur Padzik, Åbo Akademi University, 11th of February 2013:
JNK, a versatile regulator of kinesin-1 transport and cytoskeleton dynamics
Gunilla Högnäs, University of Turku, 8th of February, 2013:
Integrins in Tumorigenesis and Cancer Cell Invasion
Tapio Lönnberg, University of Turku, 26th of October, 2012:
System-wide approaches to uncover Th2 cell lineage commitment
Elisa Närvä, University of Turku, 19th of October, 2012:
Pluripotency and genetic stability of human pluripotent stem cells
Krista Rantanen, University of Turku, 12th of October, 2012:
The Dual Role of HIF Hydroxylase PHD3 in Cancer Cell Survival
High-throughput confocal microscopy
Wednesday, December 18 at 14:00
Turku Center for Biotechnology seminar room, BioCity B stairs, 5th floor
Infektimeetingit syksy 2013
Wednesday, December 18 at 17:30 - 19:00
Auditorium of Microbiological Institute, Kiinamyllynkatu 13
Dr. Olli Raitakari:
Childhood Risk Factors and Adult Cardio-Metabolic Outcomes - Insights from International Cohort Studies
Tuesday, January 7 at 12:15
Mauno Koivisto Centre Lecture Room, BioCity