Stem Cells

Human embryonic stem cells (hESC) have a unique capacity to
differentiate to any type of cell or tissue providing an enormous
potential for therapeutic applications. Our goal is to elucidate the
molecular mechanisms regulating self renewal and pluripotency of hESC.
We have identified novel genes and signaling pathways characteristic for
the pluripotent hESC based on a genome wide transcriptome analyses of
hESC. Current work aims at further characterization and functional
analysis of a panel of selected factors in the maintenance of
undifferentiated status of hESC.