University of Turku Åbo Akademi

Turku Centre for Biotechnology

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    • - Death Receptor Signaling
    • - Intermediate Filaments and Signaling
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    • - Eriksson Lab
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Research > Research areas > Cytoskeletal and survival signaling

Cytoskeletal and survival signaling

Group Leader

John Eriksson
Professor
Department of Biosciences
Åbo Akademi University
john.eriksson[at]abo.fi  john.eriksson[at]btk.fi 

Contact Information

Turku Centre for Biotechnology
P.O. Box 123, BioCity
(Street addr. Tykistökatu 6 B)
FIN-20521 Turku, Finland

+358-2-333-8036 or +358-2-215-3313 (John Eriksson)

+358-2-333-8603 (Departmental office)
+358-2-333-8096 or -8097 (laboratories)
+358-2-333-8621 or +358-2-215-4054 (student offices)
+358-2-333-8000 (Fax Attn. John Eriksson)

The 24th Sigrid Juselius Symposium

Research Area and Interests

Post-translational modifications (PTMs) modulate the activity of most eukaryotic proteins and are responsible for producing highly complex proteomes from relatively simple genomes. We use a selection of signaling networks that represent the core of our expertise to identify PTM targets and interactions when a cell is embarking upon fate-determining responses, such as activating defense and survival mechanisms or triggering death machineries.  Our main models are apoptotic, stress-mediated, and cytoskeletal signaling and we are also interested in their interrelationship. By exploring the interactions between these completely different signaling modalities, we hope to advance our understanding how critical intracellular signals are processed and integrated.

Projects

Signal transduction in receptor-mediated apoptosis

Intermediate filaments as signaling determinants

Technology transfer

Group Members

John Eriksson
Tomoko Asaoka
Fang "Rose" Cheng
Saima Ferraris
Josef Gullmets
Claire Hyder
Kimmo Isoniemi
Rajendran Senthil Kumar
Julia Lindqvist
Ponnuswamy Mohanasundaram
Beata Paziewska
Preethy Paul
Praseet Poduval
Joanna Pylvänäinen
John Russell
Helena Saarento
Elin Torvaldson

Funding

The Academy of Finland, Tekes, European Union, Sigrid Juselius Foundation, Åbo Akademi University Foundation, Finnish Cancer Foundations

Selected publications

  • Turku Centre for Biotechnology
  • Tykistokatu 6
  • FI-20520 Turku
  • Finland
  • (02) 333 8603