Publications

2017

Loukovaara S, Sandholm J, Aalto K, Liukkonen J, Jalkanen S, Yegutkin GG. Deregulation of ocular nucleotide homeostasis in patients with diabetic retinopathy. J Mol Med (Berl). 2017 Feb;95(2):193-204.

Peippo M, Gardberg M, Lamminen T, Kaipio K, Carpén O, Heuser VD. FHOD1 formin is upregulated in melanomas and modifies proliferation and tumor growth. Exp Cell Res. 2017 Jan 1;350(1):267-278.

Peuhu E, Kaukonen R, Lerche M, Saari M, Guzmán C, Rantakari P, De Franceschi N, Wärri A, Georgiadou M, Jacquemet G, Mattila E, Virtakoivu R, Liu Y, Attieh Y, Silva KA, Betz T, Sundberg JP, Salmi M, Deugnier MA, Eliceiri KW, Ivaska J. SHARPIN regulates collagen architecture and ductal outgrowth in the developing mouse mammary gland. EMBO J. 2017 Jan 17;36(2):165-182.

Salmi M, Jalkanen S, Germain RN. Allergen-Induced CD4+ T Cell Cytokine Production within Airway Mucosal Dendritic Cell-T Cell Clusters Drives the Local Recruitment of Myeloid Effector Cells. J Immunol. 2017 Jan 15;198(2):895-907.

Uusitalo E, Kallionpää RA, Kurki S, Rantanen M, Pitkäniemi J, Kronqvist P, Härkönen P, Huovinen R, Carpen O, Pöyhönen M, Peltonen S, Peltonen J. Breast cancer in neurofibromatosis type 1: overrepresentation of unfavourable prognostic factors. Br J Cancer. 2017 Jan 17;116(2):211-217.

Veres TZ, Kopcsányi T, van Panhuys N, Gerner MY, Liu Z, Rantakari P, Dunkel J, Miyasaka M, Salmi M, Jalkanen S, Germain RN. Allergen-Induced CD4+ T Cell Cytokine Production within Airway Mucosal Dendritic Cell-T Cell Clusters Drives the Local Recruitment of Myeloid Effector Cells. J Immunol. 2017 Jan 15;198(2):895-907.

2016

Bendre A, Büki KG, Määttä JA. Fam3c modulates osteogenic differentiation by down-regulating Runx2. Differentiation. 2016 Nov 30;93:50-57.

Bersanini L, Allahverdiyeva Y, Battchikova N, Heinz S, Lespinasse M, Ruohisto E, Mustila H, Nickelsen J, Vass I, Aro EM. Dissecting the Photoprotective Mechanism Encoded by the flv4-2 Operon: a Distinct Contribution of Sll0218 in Photosystem II Stabilization. Plant Cell Environ. 2016 Dec 7.

Björk JK, Åkerfelt M, Joutsen J, Puustinen MC, Cheng F, Sistonen L, Nees M. Heat-shock factor 2 is a suppressor of prostate cancer invasion.Oncogene. 2016 Apr 7;35(14):1770-84.

Blaževitš O, Mideksa YG, Šolman M, Ligabue A, Ariotti N, Nakhaeizadeh H, Fansa EK, Papageorgiou AC, Wittinghofer A, Ahmadian MR, Abankwa D. Galectin-1 dimers can scaffold Raf-effectors to increase H-ras nanoclustering. Sci Rep. 2016 Apr 18;6:24165.

Cheng F, Shen Y, Mohanasundaram P, Lindström M, Ivaska J, Ny T, Eriksson JE. Vimentin coordinates fibroblast proliferation and keratinocyte differentiation in wound healing via TGF-β-Slug signaling. Proc Natl Acad Sci U S A. 2016 Jul 26;113(30):E4320-7.

Côme C, Cvrljevic A, Khan MM, Treise I, Adler T, Aguilar-Pimentel JA, Au-Yeung B, Sittig E, Laajala TD, Chen Y, Oeder S, Calzada-Wack J, Horsch M, Aittokallio T, Busch DH, Ollert MW, Neff F, Beckers J, Gailus-Durner V, Fuchs H, Hrabě de Angelis M, Chen Z, Lahesmaa R, Westermarck J. CIP2A Promotes T-Cell Activation and Immune Response to Listeria monocytogenes Infection. PLoS One. 2016 Apr 21;11(4):e0152996.

Da Ros M, Lehtiniemi T, Olotu O, Fischer D, Zhang FP, Vihinen H, Jokitalo E, Sironen A, Toppari J, Kotaja N. FYCO1 and autophagy control the integrity of the haploid male germ cell-specific RNP granules. Autophagy. 2016 Dec 8:1-20.

De Franceschi N, Arjonen A, Elkhatib N, Denessiouk K, Wrobel AG, Wilson TA, Pouwels J, Montagnac G, Owen DJ, Ivaska J. Selective integrin endocytosis is driven by interactions between the integrin α-chain and AP2. Nat Struct Mol Biol. 2016 Feb;23(2):172-9.

Deguchi T, Alanne MH, Fazeli E, Fagerlund KM, Pennanen P, Lehenkari P, Hänninen PE, Peltonen J, Näreoja T. In vitro model of bone to facilitate measurement of adhesion forces and super-resolution imaging of osteoclasts. Sci Rep. 2016 Mar 3;6:22585.

Desai D, Prabhakar N, Mamaeva V, Karaman DŞ, Lähdeniemi IA, Sahlgren C, Rosenholm JM, Toivola DM. Targeted modulation of cell differentiation in distinct regions of the gastrointestinal tract via oral administration of differently PEG-PEI functionalized mesoporous silica nanoparticles. Int J Nanomedicine. 2016 Jan 18;11:299-313.

Dirihan S, Helander M, Väre H, Gundel PE, Garibaldi LA, Irisarri JG, Saloniemi I, Saikkonen K.Geographic Variation in Festuca rubra L. Ploidy Levels and Systemic Fungal Endophyte Frequencies. PLoS One. 2016 Nov 15;11(11):e0166264.

Guzmán C, Oetken-Lindholm C, Abankwa D. Automated High-Throughput Fluorescence Lifetime Imaging Microscopy to Detect Protein-Protein Interactions. J Lab Autom. 2016 Apr;21(2):238-45.

Helenius TO, Antman CA, Asghar MN, Nyström JH, Toivola DM. Keratins Are Altered in Intestinal Disease-Related Stress Responses. Cells. 2016 Sep 10;5(3).

Iftakhar-E-Khuda I, Fair-Mäkelä R, Kukkonen-Macchi A, Elima K, Karikoski M, Rantakari P, Miyasaka M, Salmi M, Jalkanen S. Gene-expression profiling of different arms of lymphatic vasculature identifies candidates for manipulation of cell traffic. Proc Natl Acad Sci U S A. 2016 Sep 20;113(38):10643-8.

Jacquemet G, Baghirov H, Georgiadou M, Sihto H, Peuhu E, Cettour-Janet P, He T, Perälä M, Kronqvist P, Joensuu H, Ivaska J. L-type calcium channels regulate filopodia stability and cancer cell invasion downstream of integrin signalling. Nat Commun. 2016 Dec 2;7:13297.

Kalhori V, Magnusson M, Asghar MY, Pulli I, Törnquist K. FTY720 (Fingolimod) attenuates basal and sphingosine-1-phosphate-evoked thyroid cancer cell invasion. Endocr Relat Cancer. 2016 May;23(5):457-68.

Kaukonen R, Mai A, Georgiadou M, Saari M, De Franceschi N, Betz T, Sihto H, Ventelä S, Elo L, Jokitalo E, Westermarck J, Kellokumpu-Lehtinen PL, Joensuu H, Grenman R, Ivaska J. Normal stroma suppresses cancer cell proliferation via mechanosensitive regulation of JMJD1a-mediated transcription. Nat Commun. 2016 Aug 4;7:12237.

Kaur A, Denisova OV, Qiao X, Jumppanen M, Peuhu E, Ahmed SU, Raheem O, Haapasalo H, Eriksson J, Chalmers AJ, Laakkonen P, Westermarck J. PP2A Inhibitor PME-1 Drives Kinase Inhibitor Resistance in Glioma Cells. Cancer Res. 2016 Dec 1;76(23):7001-7011.

Koho S, Fazeli E, Eriksson JE, Hänninen PE. Image Quality Ranking Method for Microscopy.Sci Rep. 2016 Jul 1;6:28962.

Laurila JP, Laukkanen MO, Joensuu H, Salmi M, Jalkanen S. Leukocyte trafficking is not affected by multikinase inhibitors sunitinib or sorafenib in mice. Int J Cancer. 2016 Nov 15;139(10):2270-6.

Mamaeva V, Niemi R, Beck M, Özliseli E, Desai D, Landor S, Gronroos T, Kronqvist P, Pettersen IK, McCormack E, Rosenholm JM, Linden M, Sahlgren C. Inhibiting Notch Activity in Breast Cancer Stem Cells by Glucose Functionalized Nanoparticles Carrying γ-secretase Inhibitors. Mol Ther. 2016 May;24(5):926-36.

Mattila M, Koskenvuo J, Söderström M, Eerola K, Savontaus M. Intramyocardial injection of SERCA2a-expressing lentivirus improves myocardial function in doxorubicin-induced heart failure. J Gene Med. 2016 Jul;18(7):124-33.

Mohammad H, Marchisella F, Ortega-Martinez S, Hollos P, Eerola K, Komulainen E, Kulesskaya N, Freemantle E, Fagerholm V, Savontous E, Rauvala H, Peterson BD, van Praag H, Coffey ET. JNK1 controls adult hippocampal neurogenesis and imposes cell-autonomous control of anxiety behaviour from the neurogenic niche. Mol Psychiatry. 2016 Nov 15.

Najumudeen AK, Jaiswal A, Lectez B, Oetken-Lindholm C, Guzmán C, Siljamäki E, Posada IM, Lacey E, Aittokallio T, Abankwa D. Cancer stem cell drugs target K-ras signaling in a stemness context. Oncogene. 2016 Oct 6;35(40):5248-5262.

Nissinen L, Siljamäki E, Riihilä P, Piipponen M, Farshchian M, Kivisaari A, Kallajoki M, Raiko L, Peltonen J, Peltonen S, Kähäri VM. Expression of claudin-11 by tumor cells in cutaneous squamous cell carcinoma is dependent on the activity of p38δ. Exp Dermatol. 2016 Dec 19.

Näreoja T, Deguchi T, Christ S, Peltomaa R, Prabhakar N, Fazeli E, Perälä N, Rosenholm JM, Arppe R, Soukka T, Schaeferling M. Ratiometric sensing and imaging of intracellular pH using polyethyleneimine-coated photon upconversion nanoprobes. Anal Chem. 2016 Dec 15.

Åkerfelt M, Bayramoglu N, Robinson S, Toriseva M, Schukov HP, Härmä V, Virtanen J, Sormunen R, Kaakinen M, Kannala J, Eklund L, Heikkilä J, Nees M. Automated tracking of tumor-stroma morphology in microtissues identifies functional targets within the tumor microenvironment for therapeutic intervention. Oncotarget. 2015 Oct 6;6(30):30035-56.

Padzik A, Deshpande P, Hollos P, Franker M, Rannikko EH, Cai D, Prus P, Mågård M, Westerlund N, Verhey KJ, James P, Hoogenraad CC, Coffey ET. KIF5C S176 Phosphorylation Regulates Microtubule Binding and Transport Efficiency in Mammalian Neurons. Front Cell Neurosci. 2016 Mar 15;10:57.

Piipponen M, Nissinen L, Farshchian M, Riihilä P, Kivisaari A, Kallajoki M, Peltonen J, Peltonen S, Kähäri VM. Long Noncoding RNA PICSAR Promotes Growth of Cutaneous Squamous Cell Carcinoma by Regulating ERK1/2 Activity. J Invest Dermatol. 2016 Aug;136(8):1701-10.

Posada IM, Serulla M, Zhou Y, Oetken-Lindholm C, Abankwa D, Lectez B. ASPP2 Is a Novel Pan-Ras Nanocluster Scaffold. PLoS One. 2016 Jul 20;11(7):e0159677.

Potorac I, Rivero-Müller A, Trehan A, Kiełbus M, Jozwiak K, Pralong F, Hafidi A, Thiry A, Ménagé JJ, Huhtaniemi I, Beckers A, Daly AF. A vital region for human glycoprotein hormone trafficking revealed by an LHB mutation. J Endocrinol. 2016 Dec;231(3):197-207.

Prabhakar N, Zhang J, Desai D, Casals E, Gulin-Sarfraz T, Näreoja T, Westermarck J, Rosenholm JM. Stimuli-responsive hybrid nanocarriers developed by controllable integration of hyperbranched PEI with mesoporous silica nanoparticles for sustained intracellular siRNA delivery. Int J Nanomedicine. 2016 Dec 8;11:6591-6608.

Rahkonen N, Stubb A, Malonzo M, Edelman S, Emani MR, Närvä E, Lähdesmäki H, Ruohola-Baker H, Lahesmaa R, Lund R. Mature Let-7 miRNAs fine tune expression of LIN28B in pluripotent human embryonic stem cells. Stem Cell Res. 2016 Nov;17(3):498-503.

Rantakari P, Patten DA, Valtonen J, Karikoski M, Gerke H, Dawes H, Laurila J, Ohlmeier S, Elima K, Hübscher SG, Weston CJ, Jalkanen S, Adams DH, Salmi M, Shetty S. Stabilin-1 expression defines a subset of macrophages that mediate tissue homeostasis and prevent fibrosis in chronic liver injury. Proc Natl Acad Sci U S A. 2016 Aug 16;113(33):9298-303.

Rantakari P, Jäppinen N, Lokka E, Mokkala E, Gerke H, Peuhu E, Ivaska J, Elima K, Auvinen K, Salmi M. Fetal liver endothelium regulates the seeding of tissue-resident macrophages. Nature. 2016 Oct 20;538(7625):392-396.

Ratcliffe CD, Sahgal P, Parachoniak CA, Ivaska J, Park M. Regulation of Cell Migration and β1 Integrin Trafficking by the Endosomal Adaptor GGA3. Traffic. 2016 Jun;17(6):670-88.

Rosenholm JM, Gulin-Sarfraz T, Mamaeva V, Niemi R, Özliseli E, Desai D, Antfolk D, von Haartman E, Lindberg D, Prabhakar N, Näreoja T, Sahlgren C. Prolonged Dye Release from Mesoporous Silica-Based Imaging Probes Facilitates Long-Term Optical Tracking of Cell Populations In Vivo. Small. 2016 Mar 23;12(12):1578-92.

Salmela M, Rappu P, Lilja J, Niskanen H, Taipalus E, Jokinen J, Heino J. Tumor promoter PMA enhances kindlin-2 and decreases vimentin recruitment into cell adhesion sites. Int J Biochem Cell Biol. 2016 Sep;78:22-30.

Santio NM, Landor SK, Vahtera L, Ylä-Pelto J, Paloniemi E, Imanishi SY, Corthals G, Varjosalo M, Manoharan GB, Uri A, Lendahl U, Sahlgren C, Koskinen PJ. Phosphorylation of Notch1 by Pim kinases promotes oncogenic signaling in breast and prostate cancer cells. Oncotarget. 2016 Jul 12;7(28):43220-43238.

Santio NM, Salmela M, Arola H, Eerola SK, Heino J, Rainio EM, Koskinen PJ. The PIM1 kinase promotes prostate cancer cell migration and adhesion via multiple signalling pathways. Exp Cell Res. 2016 Mar 15;342(2):113-24.

Sareila O, Hagert C, Rantakari P, Poutanen M, Holmdahl R. Direct Comparison of a Natural Loss-Of-Function Single Nucleotide Polymorphism with a Targeted Deletion in the Ncf1 Gene Reveals Different Phenotypes. PLoS One. 2015 Nov 3;10(11):e0141974.

Senthilkumar R, Karaman DŞ, Paul P, Björk EM, Odén M, Eriksson JE, Rosenholm JM. Targeted delivery of a novel anticancer compound anisomelic acid using chitosan-coated porous silica nanorods for enhancing the apoptotic effect. Biomater Sci. 2015 Jan;3(1):103-11.

Siljamäki E, Abankwa D. SPRED1 Interferes with K-ras but Not H-ras Membrane Anchorage and Signaling. Mol Cell Biol. 2016 Sep 26;36(20):2612-25.

Takeda A, Hossain MS, Rantakari P, Simmons S, Sasaki N, Salmi M, Jalkanen S, Miyasaka M. Thymocytes in Lyve1-CRE/S1pr1f/f Mice Accumulate in the Thymus due to Cell-Intrinsic Loss of Sphingosine-1-Phosphate Receptor Expression. Front Immunol. 2016 Nov 8;7:489.

Tambe M, Pruikkonen S, Mäki-Jouppila J, Chen P, Elgaaen BV, Straume AH, Huhtinen K, Cárpen O, Lønning PE, Davidson B, Hautaniemi S, Kallio MJ. Novel Mad2-targeting miR-493-3p controls mitotic fidelity and cancer cells’ sensitivity to paclitaxel. Oncotarget. 2016 Mar 15;7(11):12267-85.

Toivonen R, Kong L, Rasool O, Lund RJ, Lahesmaa R, Hänninen A. Activation of Plasmacytoid Dendritic Cells in Colon-Draining Lymph Nodes during Citrobacter rodentium Infection Involves Pathogen-Sensing and Inflammatory Pathways Distinct from Conventional Dendritic Cells. J Immunol. 2016 Jun 1;196(11):4750-9.

Valta MP, Zhao H, Saar M, Tuomela J, Nolley R, Linxweiler J, Sandholm J, Lehtimäki J, Härkönen P, Coleman I, Nelson PS, Corey E, Peehl DM. Spheroid culture of LuCaP 136 patient-derived xenograft enables versatile preclinical models of prostate cancer. Clin Exp Metastasis. 2016 Apr;33(4):325-37.

Vega Erramuspe IB, Fazeli E, Näreoja T, Trygg J, Hänninen P, Heinze T, Fardim P. Advanced Cellulose Fibers for Efficient Immobilization of Enzymes. Biomacromolecules. 2016 Oct 10;17(10):3188-3197.

Veres TZ, Kopcsányi T, van Panhuys N, Gerner MY, Liu Z, Rantakari P, Dunkel J, Miyasaka M, West G, Gullmets J, Virtanen L, Li SP, Keinänen A, Shimi T, Mauermann M, Heliö T, Kaartinen M, Ollila L, Kuusisto J, Eriksson JE, Goldman RD, Herrmann H, Taimen P. Deleterious assembly of the lamin A/C mutant p.S143P causes ER stress in familial dilated cardiomyopathy. J Cell Sci. 2016 Jul 15;129(14):2732-43.

2015

Alanko J, Mai A, Jacquemet G, Schauer K, Kaukonen R, Saari M, Goud B, Ivaska J. Integrin endosomal signalling suppresses anoikis. Nat Cell Biol. 2015 Nov;17(11):1412-21. Epub 2015 Oct 5.

Alastalo TP, West G, Li SP, Keinänen A, Helenius M, Tyni T, Lapatto R, Turanlahti M, Heikkilä P, Kääriäinen H, Laakso M, Mauermann M,Herrmann H, Pihkala J, Taimen P.  LMNA Mutation c.917T>G (p.L306R) Leads to Deleterious Hyper-Assembly of Lamin A/C and Associates with Severe Right Ventricular Cardiomyopathy and Premature Aging.  Hum Mutat. 2015 Jul;36(7):694-703. Epub 2015 Jun 1.

Asghar MN, Silvander JS, Helenius TO, Lähdeniemi IA, Alam C, Fortelius LE, Holmsten RO, Toivola DM. The amount of keratins matters for stress protection of the colonic epithelium. PLoS One. 2015 May 22;10(5):e0127436.

Asghar MY, Magnusson M, Kemppainen K, Sukumaran P, Löf C, Pulli I, Kalhori V, Törnquist K. Transient Receptor Potential Canonical 1 (TRPC1) Channels as Regulators of Sphingolipid and VEGF Receptor Expression: IMPLICATIONS FOR THYROID CANCER CELL MIGRATION AND PROLIFERATION. J Biol Chem. 2015 Jun 26;290(26):16116-31.

Budzyńska PM, Niemelä M, Sarapulov AV, Kyläniemi MK, Nera KP, Junttila S, Laiho A, Mattila PK, Alinikula J, Lassila O. IRF4 Deficiency Leads to Altered BCR Signalling Revealed by Enhanced PI3K Pathway, Decreased SHIP Expression and Defected Cytoskeletal Responses. Scand J Immunol. 2015 Nov;82(5):418-28.

Budzyński MA, Puustinen MC, Joutsen J, Sistonen L. Uncoupling Stress-Inducible Phosphorylation of Heat Shock Factor 1 from Its Activation. Mol Cell Biol. 2015 Jul;35(14):2530-40. Epub 2015 May 11.

Da Ros M, Hirvonen N, Olotu O, Toppari J, Kotaja N. Retromer vesicles interact with RNA granules in haploid male germ cells. Mol Cell Endocrinol. 2015 Feb 5;401:73-83.

De Franceschi N, Peuhu E, Parsons M, Rissanen S, Vattulainen I, Salmi M, Ivaska J, Pouwels J. Mutually Exclusive Roles of SHARPIN in Integrin Inactivation and NF-κB Signaling. PLoS One. 2015 Nov 3;10(11):e0143423.

Eichin D, Laurila JP, Jalkanen S, Salmi M. CD73 Activity is Dispensable for the Polarization of M2 Macrophages.  PLoS One. 2015 Aug 10;10(8):e0134721. doi: 10.1371/journal.pone.0134721. eCollection 2015.

Emani MR, Närvä E, Stubb A, Chakroborty D, Viitala M, Rokka A, Rahkonen N, Moulder R, Denessiouk K, Trokovic R, Lund R, Elo LL, Lahesmaa R. The L1TD1 protein interactome reveals the importance of post-transcriptional regulation in human pluripotency. Stem Cell Reports. 2015 Mar 10;4(3):519-28.

Hakanpää L, Sipilä T, Leppänen VM, Gautam P, Nurmi H, Jacquemet G, Eklund L, Ivaska J, Alitalo K, Saharinen P. Endothelial destabilization by angiopoietin-2 via integrin β1 activation. Nat Commun. 2015 Jan 30;6:5962.

Heinonen MT, Kanduri K, Lähdesmäki HJ, Lahesmaa R, Henttinen TA. Tubulin- and actin-associating GIMAP4 is required for IFN-γ secretion during Th cell differentiation. Immunol Cell Biol. 2015 Feb;93(2):158-66.

Heinonen MT, Laine AP, Söderhäll C, Gruzieva O, Rautio S, Melén E, Pershagen G, Lähdesmäki HJ, Knip M, Ilonen J, Henttinen TA, Kere J, Lahesmaa R; Finnish Pediatric Diabetes Registry. GIMAP GTPase family genes: potential modifiers in autoimmune diabetes, asthma, and allergy. J Immunol. 2015 Jun 15;194(12):5885-94.

Helenius TO, Misiorek JO, Nyström JH, Fortelius LE, Habtezion A, Liao J, Asghar MN, Zhang H, Azhar S, Omary MB, Toivola DM. Keratin 8 absence down-regulates colonocyte HMGCS2 and modulates colonic ketogenesis and energy metabolism. Mol Biol Cell. 2015 Jun 15;26(12):2298-310.

Hyder CL, Kemppainen K, Isoniemi KO, Imanishi SY, Goto H, Inagaki M, Fazeli E, Eriksson JE, Törnquist K. Sphingolipids inhibit vimentin-dependent cell migration.  J Cell Sci. 2015 Jun 1;128(11):2057-69.

Högel H, Miikkulainen P, Bino L, Jaakkola PM. Hypoxia inducible prolyl hydroxylase PHD3 maintains carcinoma cell growth by decreasing the stability of p27. Mol Cancer. 2015 Jul 30;14(1):143.

Kankaanpää P, Tiitta S, Bergman L, Puranen AB, von Haartman E, Lindén M, Heino J. Cellular recognition and macropinocytosis-like internalization of nanoparticles targeted to integrin α2β1. Nanoscale. 2015 Nov 14;7(42):17889-901.

Kaur A, Elzagheid A, Birkman EM, Avoranta T, Kytölä V, Korkeila E, Syrjänen K, Westermarck J, Sundström J. Protein phosphatase methylesterase-1 (PME-1) expression predicts a favorable clinical outcome in colorectal cancer. Cancer Med. 2015 Dec;4(12):1798-808. Epub 2015 Sep 17.

Knaapi J, Kiviranta R, Laine J, Kääpä P, Lukkarinen H. Cathepsin K overexpression modifies lung development in newborn mice. Pediatr Pulmonol. 2015 Feb;50(2):164-72.

Konert G, Trotta A, Kouvonen P, Rahikainen M, Durian G, Blokhina O, Fagerstedt K, Muth D, Corthals GL, Kangasjärvi S. Protein phosphatase 2A (PP2A) regulatory subunit B’γ interacts with cytoplasmic ACONITASE 3 and modulates the abundance of AOX1A and AOX1D in Arabidopsis thaliana. New Phytol. 2015 Feb;205(3):1250-63.

Korhonen HM, Yadav RP, Da Ros M, Chalmel F, Zimmermann C, Toppari J, Nef S, Kotaja N. DICER Regulates the Formation and Maintenance of Cell-Cell Junctions in the Mouse Seminiferous Epithelium. Biol Reprod. 2015 Dec;93(6):139. Epub 2015 Oct 28.

Lindqvist J, Imanishi SY, Torvaldson E, Malinen M, Remes M, Örn F, Palvimo JJ, Eriksson JE. Cyclin-dependent kinase 5 acts as a critical determinant of AKT-dependent proliferation and regulates differential gene expression by the androgen receptor in prostate cancer cells. Mol Biol Cell. 2015 Jun 1;26(11):1971-84.

Lynch F, Santana-Sanchez A, Jämsä M, Sivonen K, Aro EM, Allahverdiyeva Y. Screening native isolates of cyanobacteria and a green alga for integrated wastewater treatment, biomass accumulation and neutral lipid production. Algal Res. 2015.

Myant K, Qiao X, Halonen T, Come C, Laine A, Janghorban M, Partanen JI, Cassidy J, Ogg EL, Cammareri P, Laiterä T, Okkeri J, Klefström 5, Sears RC, Sansom OJ, Westermarck J. Serine 62-Phosphorylated MYC Associates with Nuclear Lamins and Its Regulation by CIP2A Is Essential for Regenerative Proliferation. Cell Rep. 2015 Aug 11;12(6):1019-31.

Mäki-Jouppila JH, Pruikkonen S, Tambe MB, Aure MR, Halonen T, Salmela AL, Laine L, Børresen-Dale AL, Kallio MJ. MicroRNA let-7b regulates genomic balance by targeting Aurora B kinase. Mol Oncol. 2015 Jan 27.

Najumudeen AK, Guzmán C, Posada IM, Abankwa D. Rab-NANOPS: FRET biosensors for Rab membrane nanoclustering and prenylation detection in mammalian cells. Methods Mol Biol. 2015;1298:29-45.

Najumudeen AK, Posada IM, Lectez B, Zhou Y, Landor SK, Fallarero A, Vuorela P, Hancock J, Abankwa D1. Phenotypic Screening Identifies Protein Synthesis Inhibitors as H-Ras-Nanocluster-Increasing Tumor Growth Inducers. Biochemistry. 2015 Dec 15;54(49):7212-21.

Niemelä E, Desai D, Nkizinkiko Y, Eriksson JE, Rosenholm JM. Sugar-decorated mesoporous silica nanoparticles as delivery vehicles for the poorly soluble drug celastrol enables targeted induction of apoptosis in cancer cells. Eur J Pharm Biopharm. 2015 Oct;96:11-21. Epub 2015 Jul 14.

Pokharel YR, Saarela J, Szwajda A, Rupp C, Rokka A, Lal Kumar Karna S, Teittinen K, Corthals G, Kallioniemi, Wennerberg K, Aittokallio 2, Westermarck J. Relevance Rank Platform (RRP) for Functional Filtering of High Content Protein-Protein Interaction Data. Mol Cell Proteomics. 2015 Dec;14(12):3274-83.

Prabhakar N, Näreoja T, von Haartman E, Şen Karaman D, Burikov SA, Dolenko TA, Deguchi T, Mamaeva V, Hänninen PE, Vlasov II, Shenderova OA, Rosenholm JM. Functionalization of graphene oxide nanostructures improves photoluminescence and facilitates their use as optical probes in preclinical imaging. Nanoscale. 2015 Jun 21;7(23):10410-20.

Rantakari P, Auvinen K, Jäppinen N, Kapraali M, Valtonen J, Karikoski M, Gerke H, Iftakhar-E-Khuda I, Keuschnigg J, Umemoto E, Tohya K, Miyasaka M, Elima K, Jalkanen S, Salmi M. The endothelial protein PLVAP in lymphatics controls the entry of lymphocytes and antigens into lymph nodes. Nat Immunol. 2015 Apr;16(4):386-96.

Rivero-Müller A, Potorac I, Pintiaux A, Daly AF, Thiry A, Rydlewski C, Nisolle M, Parent AS,Huhtaniemi I, Beckers A. A novel inactivating mutation of the luteinizing hormone/chorionic gonadotrophin receptor (LHCGR) with impaired membrane trafficking leading to Leydig cell hypoplasia type 1. Eur J Endocrinol. 2015 Mar 20.

Rotgers E, Cisneros-Montalvo S, Jahnukainen K, Sandholm J, Toppari J, Nurmio M. A detailed protocol for a rapid analysis of testicular cell populations using flow cytometry. Andrology. 2015 Sep;3(5):947-55.

Rotgers E, Nurmio M, Pietilä E, Cisneros-Montalvo S, Toppari J. E2F1 controls germ cell apoptosis during the first wave of spermatogenesis. Andrology. 2015 Sep;3(5):1000-14.

Santio NM, Eerola SK, Paatero I, Yli-Kauhaluoma J, Anizon F, Moreau P, Tuomela J, Härkönen P, Koskinen PJ. Pim Kinases Promote Migration and Metastatic Growth of Prostate Cancer Xenografts. PLoS One. 2015 Jun 15;10(6):e0130340. eCollection 2015.

Šolman M, Ligabue A, Blaževitš O, Jaiswal A, Zhou Y, Liang H, Lectez B, Kopra K, Guzmán C, Härmä H, Hancock JF, Aittokallio T, Abankwa D. Specific cancer-associated mutations in the switch III region of Ras increase tumorigenicity by nanocluster augmentation. Elife. 2015 Aug 14;4:e08905.

Sousa S, Brion R, Lintunen M, Kronqvist P, Sandholm J, Mönkkönen J, Kellokumpu-Lehtinen PL, Lauttia S, Tynninen O, Joensuu H, Heymann D, Määttä JA. Human breast cancer cells educate macrophages toward the M2 activation status. Breast Cancer Res. 2015 Aug 5;17(1):101.

Toivola DM, Habtezion A, Misiorek JO, Zhang L, Nyström JH, Sharpe O, Robinson WH, Kwan R, Omary MB. Absence of keratin 8 or 18 promotes antimitochondrial autoantibody formation in aging male mice. FASEB J. 2015 Dec;29(12):5081-9.

Torvaldson E, Kochin V, Eriksson JE. Phosphorylation of lamins determine their structural properties and signaling functions. Nucleus. 2015;6(3):166-71.

Ventelä S, Sittig E, Mannermaa L, Mäkelä JA, Kulmala J, Löyttyniemi E, Strauss L, Cárpen O,Toppari J, Grénman R, Westermarck J. CIP2A is an Oct4 target gene involved in head and neck squamous cell cancer oncogenicity and radioresistance. Oncotarget. 2015 Jan 1;6(1):144-58.

Virtakoivu R, Mai A, Mattila E, De Franceschi N, Imanishi SY, Corthals G, Kaukonen R, Saari M, Cheng F, Torvaldson E, Kosma VM, Mannermaa A, Muharram G, Gilles C, Eriksson J, Soini Y, Lorens JB, Ivaska J. Vimentin-ERK Signaling Uncouples Slug Gene Regulatory Function. Cancer Res. 2015 Jun 1;75(11):2349-62.

Virtanen H, Autio A, Siitonen R, Liljenbäck H, Saanijoki T, Lankinen P, Mäkilä J, Käkelä M, Teuho J, Savisto N, Jaakkola K, Jalkanen S, Roivainen A. 68Ga-DOTA-Siglec-9–a new imaging tool to detect synovitis. Arthritis Res Ther. 2015 Nov 3;17:308.

Wahlroos T, Susi P. Differential Effects of Viral Coat Protein on Induction of Hypersensitive Response and Systemic Movement of Tobacco Mosaic Virus and Tobacco Mild Green Mosaic Virus in Nicotiana megalosiphon. J Plant Pathol Microb 2015, 6:1.

Weber-Boyvat M, Kentala H, Lilja J, Vihervaara T, Hanninen R, Zhou Y, Peränen J, Nyman TA, Ivaska J, Olkkonen VM. OSBP-related protein 3 (ORP3) coupling with VAMP-associated protein A regulates R-Ras activity. Exp Cell Res. 2015 Feb 15;331(2):278-91.

Weston CJ, Shepherd EL, Claridge LC, Rantakari P, Curbishley SM, Tomlinson JW, Hubscher SG, Reynolds GM, Aalto K, Anstee QM, Jalkanen S, Salmi M, Smith DJ, Day CP, Adams DH. Vascular adhesion protein-1 promotes liver inflammation and drives hepatic fibrosis. J Clin Invest. 2015 Feb;125(2):501-20.

Yegutkin G, Auvinen K, Rantakari P, Hollmén M, Karikoski M, Grénman R, Elima K, Jalkanen S, Salmi M. Ecto-5′-nucleotidase/CD73 enhances endothelial barrier function and sprouting in blood but not lymphatic vasculature. Eur J Immunol. 2015 Feb;45(2):562-73.

2014

Alpay K, Farshchian M, Tuomela J, Sandholm J, Aittokallio K, Siljamäki E, Kallio M, Kähäri VM, Hietanen S. Inhibition of c-Abl Kinase Activity Renders Cancer Cells Highly Sensitive to Mitoxantrone. PLoS One. 2014 Aug 22;9(8):e105526.

Arjonen A, Kaukonen R, Mattila E, Rouhi P, Högnäs G, Sihto H, Miller BW, Morton JP, Bucher E, Taimen P, Virtakoivu R, Cao Y, Sansom OJ, Joensuu H, Ivaska J. Mutant p53-associated myosin-X upregulation promotes breast cancer invasion and metastasis. J Clin Invest. 2014 Mar;124(3):1069-82.

Asghar MN, Emani R, Alam C, Helenius TO, Grönroos TJ, Sareila O, Din MU, Holmdahl R, Hänninen A, Toivola DM. In vivo imaging of reactive oxygen and nitrogen species in murine colitis. Inflamm Bowel Dis. 2014 Aug;20(8):1435-47.

Auvinen K, Jalkanen S, Salmi M. Expression and function of endothelial selectins during human development.Immunology. 2014 Nov;143(3):406-15.

Böcking D, Wiltschka O, Niinimäki J, Shokry H, Brenner R, Lindén M, Sahlgren C. Mesoporous silica nanoparticle-based substrates for cell directed delivery of Notch signalling modulators to control myoblast differentiation. Nanoscale. 2014;6(3):1490-8.

Coxon FP, Joachimiak L, Najumudeen AK, Breen G, Gmach J, Oetken-Lindholm C, Way R, Dunford JE, Abankwa D, Błażewska KM. Synthesis and characterization of novel phosphonocarboxylate inhibitors of RGGT. Eur J Med Chem. 2014 Sep 12;84:77-89.

Dunkel J, Aguilar-Pimentel JA, Ollert M, Fuchs H, Gailus-Durner V, de Angelis MH, Jalkanen S, Salmi M, Veres TZ. Endothelial amine oxidase AOC3 transiently contributes to adaptive immune responses in the airways. Eur J Immunol. 2014 Nov;44(11):3232-9.

Elsing AN, Aspelin C, Björk JK, Bergman HA, Himanen SV, Kallio MJ, Roos-Mattjus P, Sistonen L..  Expression of HSF2 decreases in mitosis to enable stress-inducible transcription and cell survival. J Cell Biol. 2014 Sep 15;206(6):735-49.

Ermakova M1, Battchikova N1, Richaud P2, Leino H1, Kosourov S1, Isojärvi J1, Peltier G2, Flores E3, Cournac L2, Allahverdiyeva Y4, Aro EM4. Heterocyst-specific flavodiiron protein Flv3B enables oxic diazotrophic growth of the filamentous cyanobacterium Anabaena sp. PCC 7120. Proc Natl Acad Sci U S A. 2014 Jul 29;111(30):11205-10.

Gardberg M, Heuser VD, Iljin K, Kampf C, Uhlen M, Carpén O. Characterization of Leukocyte Formin FMNL1 Expression in Human Tissues. J Histochem Cytochem. 2014 Apr 3;62(6):460-470.

Goldgur Y, Susi P, Karelehto E, Sanmark H, Lamminmäki U, Oricchio E, Wendel HG, Nikolov DB, Himanen JP. Generation and characterization of a single-chain anti-EphA2 antibody. Growth Factors. 2014 Dec;32(6):214-22.

Gulin-Sarfraz Tina,  Jawad Sarfraz,  Didem Şen Karaman,   Jixi Zhang,   Christina Oetken-Lindholm,   Alain Duchanoy,   Jessica M. Rosenholm and   Daniel Abankwa. FRET-reporter nanoparticles to monitor redox-induced intracellular delivery of active compounds. RSC Adv., 2014,4, 16429-16437.

Guzmán C, Solman M, Abankwa D. Nanoclustering and heterogeneous membrane diffusion of Ras studied by FRAP and RICS analysis. Methods Mol Biol. 2014;1120:307-26.

Guzmán C, Bagga M, Kaur A, Westermarck J, Abankwa D. ColonyArea: an ImageJ plugin to automatically quantify colony formation in clonogenic assays. PLoS One. 2014 Mar 19;9(3):e92444.

Guzmán C, Šolman M, Ligabue A, Blaževitš O, Andrade DM, Reymond L, Eggeling C, Abankwa D. The efficacy of Raf kinase recruitment to the GTPase H-ras depends on H-ras membrane conformer-specific nanoclustering. J Biol Chem. 2014 Apr 4;289(14):9519-33.

Heinonen MT, Kanduri K, Lähdesmäki HJ, Lahesmaa R, Henttinen TA. Tubulin- and actin-associating GIMAP4 is required for IFN-γ secretion during Th cell differentiation. Immunol Cell Biol. 2014 Oct 7.

Hyder CL, Lazaro G, Pylvänäinen JW, Roberts MW, Qvarnström SM, Eriksson JE. Nestin regulates prostate cancer cell invasion by influencing the localisation and functions of FAK and integrins. J Cell Sci. 2014 May 15;127(Pt 10):2161-73.

Kalliokoski T, Tuomela J, Haavisto L, Forsback S, Snellman A, Helin S, Grönroos TJ, Solin O,Haaparanta-Solin M. 6-[18F]fluoro-L-DOPA uptake in the rat pancreas is dependent on the tracer metabolism. Mol Imaging Biol. 2014 Jun;16(3):403-11.

Karikoski M, Marttila-Ichihara F, Elima K, Rantakari P, Hollmén M, Kelkka T, Gerke H, Huovinen V, Irjala H, Holmdahl R, Salmi M, Jalkanen S. Clever-1/stabilin-1 controls cancer growth and metastasis. Clin Cancer Res. 2014 Dec 15;20(24):6452-64.

Kochin V, Shimi T, Torvaldson E, Adam SA, Goldman A, Pack CG, Melo-Cardenas J, Imanishi SY, Goldman RD, Eriksson JE. Interphase phosphorylation of lamin A. J Cell Sci. 2014 Jun 15;127(Pt 12):2683-96.

Komulainen E, Zdrojewska J, Freemantle E, Mohammad H, Kulesskaya N, Deshpande P, Marchisella F, Mysore R, Hollos P, Michelsen KA, Mågard M, Rauvala H, James P, Coffey ET. JNK1 controls dendritic field size in L2/3 and L5 of the motor cortex, constrains soma size, and influences fine motor coordination. Front Cell Neurosci. 2014 Sep 12;8:272.

Koskinen A, Lukkarinen H, Laine J, Ahotupa M, Kääpä P, Soukka H. Delay in rat lung alveolarization after the combined exposure of maternal hyperglycemia and postnatal hyperoxia. Pediatr Pulmonol. 2014 Feb;49(2):179-88.

Kyläniemi MK, Kaukonen R, Myllyviita J, Rasool O, Lahesmaa R. The regulation and role of c-FLIP in human Th cell differentiation. PLoS One. 2014 Jul 14;9(7):e102022.

Mai A, Muharram G, Barrow-McGee R, Baghirov H, Rantala J, Kermorgant S, Ivaska J. Distinct c-Met activation mechanisms induce cell rounding or invasion through pathways involving integrins, RhoA and HIP1. J Cell Sci. 2014 May 1;127(Pt 9):1938-52.

Muharram G, Sahgal P, Korpela T, De Franceschi N, Kaukonen R, Clark K, Tulasne D, Carpén O, Ivaska J. Tensin-4-dependent MET stabilization is essential for survival and proliferation in carcinoma cells. Dev Cell. 2014 May 27;29(4):421-36. Erratum in: Dev Cell. 2014 Jun 9:29(5):629-30.

Mäkelä JA, Toppari J, Rivero-Müller A, Ventelä S. Reconstruction of mouse testicular cellular microenvironments in long-term seminiferous tubule culture. PLoS One. 2014 Mar 11;9(3):e90088.

Mäki-Jouppila JH, Laine LJ, Rehnberg J, Narvi E, Tiikkainen P, Hukasova E, Halonen P, Lindqvist A, Kallio L, Poso A, Kallio MJ. Centmitor-1, a novel acridinyl-acetohydrazide, possesses similar molecular interaction field and antimitotic cellular phenotype as rigosertib, on 01910.Na. Mol Cancer Ther. 2014 May;13(5):1054-66.

Paatero I, Seagroves TN, Vaparanta K, Han W, Jones FE, Johnson RS, Elenius K. Hypoxia-inducible factor-1α induces ErbB4 signaling in the differentiating mammary gland. J Biol Chem. 2014 Aug 8;289(32):22459-69.

Paul P, Rajendran SK, Peuhu E, Alshatwi AA, Akbarsha MA, Hietanen S, Eriksson JE. Novel action modality of the diterpenoid anisomelic acid causes depletion of E6 and E7 viral oncoproteins in HPV-transformed cervical carcinoma cells. Biochem Pharmacol. 2014 May 15;89(2):171-84.

Rotgers E, Rivero-Müller A, Nurmio M, Parvinen M, Guillou F, Huhtaniemi I, Kotaja N, Bourguiba-Hachemi S, Toppari J. Retinoblastoma protein (RB) interacts with E2F3 to control terminal differentiation of Sertoli cells. Cell Death Dis. 2014 Jun 5;5:e1274.

Siljamäki E, Raiko L, Toriseva M, Nissinen L, Näreoja T, Peltonen J, Kähäri VM, Peltonen. p38δ mitogen-activated protein kinase regulates the expression of tight junction protein ZO-1 in differentiating human epidermal keratinocytes.  Arch Dermatol Res. 2014 Mar;306(2):131-41.

Sipilä K, Haag S, Denessiouk K, Käpylä J, Peters EC, Denesyuk A, Hansen U, Konttinen Y, Johnson MS, Holmdahl R, Heino J. Citrullination of collagen II affects integrin-mediated cell adhesion in a receptor-specific manner. FASEB J. 2014 Aug;28(8):3758-68.

Sjöqvist M, Antfolk D, Ferraris S, Rraklli V, Haga C, Antila C, Mutvei A, Imanishi SY, Holmberg J, Jin S, Eriksson JE, Lendahl U, Sahlgren C. PKCζ regulates Notch receptor routing and activity in a Notch signaling-dependent manner. Cell Res. 2014 Apr;24(4):433-50.

Trehan A, Rotgers E, Coffey ET, Huhtaniemi I, Rivero-Müller A. CANDLES, an assay for monitoring GPCR induced cAMP generation in cell cultures. Cell Commun Signal. 2014 Nov 4;12(1):70.

Virtanen SS, Kukkonen-Macchi A, Vainio M, Elima K, Härkönen PL, Jalkanen S, Yegutkin GG. Adenosine inhibits tumor cell invasion via receptor-independent mechanisms. Mol Cancer Res. 2014 Dec;12(12):1863-74.

Winsel S, Mäki-Jouppila J, Tambe M, Aure MR, Pruikkonen S, Salmela AL, Halonen T, Leivonen SK, Kallio L, Børresen-Dale AL, Kallio M1. Excess of miRNA-378a-5p perturbs mitotic fidelity and correlates with breast cancer tumourigenesis in vivo. Br J Cancer. 2014 Nov 25;111(11):2142-51.

Yegutkin GG, Auvinen K, Karikoski M, Rantakari P, Gerke H, Elima K, Maksimow M, Quintero IB, Vihko P, Salmi M, Jalkanen S. Consequences of the lack of CD73 and prostatic acid phosphatase in the lymphoid organs. Mediators Inflamm. 2014;2014:485743.

2013

Alam CM, Silvander JS, Daniel EN, Tao GZ, Kvarnström SM, Alam P, Omary MB, Hänninen A, Toivola DM. Keratin 8 modulates β-cell stress responses and normoglycaemia. J Cell Sci. 2013 Dec 15;126(Pt 24):5635-44.

Arjonen A, Kaukonen R, Mattila E, Rouhi P, Högnäs G, Sihto H, Miller BW, Morton JP, Bucher E, Taimen P, Virtakoivu R, Cao Y, Sansom OJ, Joensuu H, Ivaska J. Mutant p53-associated myosin-X upregulation promotes breast cancer invasion and metastasis. J Clin Invest. 2014 Mar;124(3):1069-82.

Autio A, Vainio PJ, Suilamo S, Mali A, Vainio J, Saanijoki T, Noponen T, Ahtinen H, Luoto P, Teräs M, Jalkanen S, Roivainen A. Preclinical evaluation of a radioiodinated fully human antibody for in vivo imaging of vascular adhesion protein-1-positive vasculature in inflammation. J Nucl Med. 2013 Aug;54(8):1315-9

Bergman L, Kankaanpää P, Tiitta S, Duchanoy A, Li L, Heino J, Lindén M. Intracellular degradation of multilabeled poly(ethylene imine)-mesoporous silica-silica nanoparticles: implications for drug release. Mol Pharm. 2013 May 6;10(5):1795-803.

Castellone MD, Laatikainen LE, Laurila JP, Langella A, Hematti P, Soricelli A, Salvatore M, Laukkanen MO. Brief report: Mesenchymal stromal cell atrophy in coculture increases aggressiveness of transformed cells. Stem Cells. 2013 Jun;31(6):1218-23.

Eerola K, Nordlund W, Virtanen S, Dickens AM, Mattila M, Ruohonen ST, Chua SC Jr, Wardlaw SL,Savontaus M, Savontaus E. Lentivirus-Mediated α-Melanocyte-Stimulating Hormone Overexpression in the Hypothalamus Decreases Diet Induced Obesity in Mice. J Neuroendocrinol. 2013 Dec;25(12):1298-307.

Ermakova M, Battchikova N, Allahverdiyeva Y, Aro EM. Novel heterocyst-specific flavodiiron proteins in Anabaena sp. PCC 7120. FEBS Lett. 2013 Jan 4;587(1):82-7.

Emani R, Asghar MN, Toivonen R, Lauren L, Söderström M, Toivola DM, van Tol EA, Hänninen A. Casein hydrolysate diet controls intestinal T cell activation, free radical production and microbial colonisation in NOD mice. Diabetologia. 2013 Aug;56(8):1781-91.

Fallarero A, Skogman M, Kujala J, Rajaratnam M, Moreira VM, Yli-Kauhaluoma J, Vuorela P. (+)-Dehydroabietic Acid, an Abietane-Type Diterpene, Inhibits Staphylococcus aureus Biofilms in Vitro. Int J Mol Sci. 2013 Jun 5;14(6):12054-72.

Gardberg M, Kaipio K, Lehtinen L, Mikkonen P, Heuser VD, Talvinen K, Iljin K, Kampf C, Uhlen M, Grénman R, Koivisto M, Carpén O. FHOD1, a formin upregulated in epithelial-mesenchymal transition, participates in cancer cell migration and invasion. PLoS One. 2013 Sep 26;8(9):e74923.

Hirvonen MJ, Büki KG, Sun Y, Mulari MT, Härkönen PL, Väänänen KH. Novel interaction of Rab13 and Rab8 with endospanins. FEBS Open Bio. 2013 Jan 22;3:83-8.

Hämälistö S, Pouwels J, de Franceschi N, Saari M, Ivarsson Y, Zimmermann P, Brech A, Stenmark H, Ivaska J.  A ZO-1/α5β1-integrin complex regulates cytokinesis downstream of PKCε in NCI-H460 cells plated on fibronectin. PLoS One. 2013 Aug 13;8(8):e70696.

Jääskeläinen AE, Seppälä S, Kakko T, Jaakkola U, Kallio J. Systemic treatment with neuropeptide Y receptor Y1-antagonist enhances atherosclerosis and stimulates IL-12 expression in ApoE deficient mice. Neuropeptides. 2013 Apr;47(2):67-73.

Kaitaniemi S, Grön K, Elovaara H, Salmi M, Jalkanen S, Elima K. Functional modulation of vascular adhesion protein-1 by a novel splice variant. PLoS One. 2013;8(1):e54151.

Kalliokoski T1, Tuomela J, Haavisto L, Forsback S, Snellman A, Helin S, Grönroos TJ, Solin O, Haaparanta-Solin M. 6-[18F]fluoro-L-DOPA uptake in the rat pancreas is dependent on the tracer metabolism.  Mol Imaging Biol. 2014 Jun;16(3):403-11.

Keuschnigg J, Karinen S, Auvinen K, Irjala H, Mpindi JP, Kallioniemi O, Hautaniemi S, Jalkanen S, Salmi M. Plasticity of blood- and lymphatic endothelial cells and marker identification. PLoS One.2013 Sep 10;8(9):e74293.

Kiriazis A, Vahakoski RL, Santio NM, Arnaudova R, Eerola SK, Rainio EM, Aumüller IB, Yli-Kauhaluoma J, Koskinen PJ.Tricyclic Benzo[cd]azulenes selectively inhibit activities of Pim kinases and restrict growth of Epstein-Barr virus-transformed cells. PLoS One. 2013;8(2):e55409.

Korhonen JT, Olkkonen VM, Lahesmaa R, Puolakkainen M. ABC-cassette transporter 1 (ABCA1) expression in epithelial cells in Chlamydia pneumoniae infection. Microb Pathog. 2013 Aug-Sep;61-62:57-61.

Laine A, Sihto H, Come C, Rosenfeldt MT, Zwolinska A, Niemelä M, Khanna A, Chan EK, Kähäri VM, Kellokumpu-Lehtinen PL, Sansom OJ, Evan GI, Junttila MR, Ryan KM, Marine JC, Joensuu H, Westermarck J. Senescence sensitivity of breast cancer cells is defined by positive feedback loop between CIP2A and E2F1. Cancer Discov. 2013 Feb;3(2):182-97.

Laurén HB, Ruohonen S, Kukko-Lukjanov TK, Virta JE, Grönman M, Lopez-Picon FR, Järvelä JT, Holopainen IE. Status epilepticus alters neurogenesis and decreases the number of GABAergic neurons in the septal dentate gyrus of 9-day-old rats at the early phase of epileptogenesis. Brain Res. 2013 Jun 21;1516:33-44.

Najumudeen AK, Köhnke M, Solman M, Alexandrov K, Abankwa D. Cellular FRET-Biosensors to Detect Membrane Targeting Inhibitors of N-Myristoylated Proteins. PLoS One. 2013 Jun 18;8(6):e66425.

Nygårdas M, Paavilainen H, Müther N, Nagel CH, Röyttä M, Sodeik B, Hukkanen V. A herpes simplex virus-derived replicative vector expressing LIF limits experimental demyelinating disease and modulates autoimmunity. PLoS One. 2013 May 20;8(5):e64200.

Närvä E, Pursiheimo JP, Laiho A, Rahkonen N, Emani MR, Viitala M, Laurila K, Sahla R, Lund R, Lähdesmäki H, Jaakkola P, Lahesmaa R. Continuous hypoxic culturing of human embryonic stem cells enhances SSEA-3 and MYC levels. PLoS One.2013 Nov 13;8(11):e78847.

Peuhu E, Paul P, Remes M, Holmbom T, Eklund P, Sjöholm R, Eriksson JE. The antitumor lignan Nortrachelogenin sensitizes prostate cancer cells to TRAIL-induced cell death by inhibition of the Akt pathway and growth factor signaling. Biochem Pharmacol. 2013 Sep 1;86(5):571-83.

Pouwels J, De Franceschi N, Rantakari P, Auvinen K, Karikoski M, Mattila E, Potter C, Sundberg JP, Hogg N, Gahmberg CG, Salmi M, Ivaska J. SHARPIN regulates uropod detachment in migrating lymphocytes. Cell Rep. 2013 Nov 14;5(3):619-28.

Prabhakar N, Näreoja T, von Haartman E, Karaman DŞ, Jiang H, Koho S, Dolenko TA, Hänninen PE, Vlasov DI, Ralchenko VG, Hosomi S, Vlasov II, Sahlgren C, Rosenholm JM. Core-shell designs of photoluminescent nanodiamonds with porous silica coatings for bioimaging and drug delivery II: application. Nanoscale. 2013 May 7;5(9):3713-22.

Rantanen K, Pursiheimo JP, Högel H, Miikkulainen P, Sundström J, Jaakkola PM. p62/SQSTM1 regulates cellular oxygen sensing by attenuating PHD3 activity through aggregate sequestration and enhanced degradation. J Cell Sci. 2013 Mar 1;126(Pt 5):1144-54.

Ruuska M, Sahlberg AS, Granfors K, Penttinen MA. Phosphorylation of STAT-1 serine 727 is prolonged in HLA-B27-expressing human monocytic cells. PLoS One. 2013;8(1):e50684.

Sahlberg AS, Ruuska M, Granfors K, Penttinen MA. Altered Regulation of ELAVL1/HuR in HLA-B27-Expressing U937 Monocytic Cells. PLoS One. 2013 Jul 22;8(7):e70377.

Salmi M, Karikoski M, Elima K, Rantakari P, Jalkanen S. CD44 binds to macrophage mannose receptor on lymphatic endothelium and supports lymphocyte migration via afferent lymphatics. Circ Res. 2013 Jun 7;112(12):1577-82.

Sareila O, Jaakkola N, Olofsson P, Kelkka T, Holmdahl R. Identification of a region in p47phox/NCF1 crucial for phagocytic NADPH oxidase (NOX2) activation. J Leukoc  Biol. 2013 Mar;93(3):427-35.

Sukumaran P, Löf C, Pulli I, Kemppainen K, Viitanen T, Törnquist K. Significance of the transient receptor potential canonical 2 (TRPC2) channel in the regulation of rat thyroid FRTL-5 cell proliferation, migration, adhesion and invasion. Mol Cell Endocrinol. 2013 Jul 15;374(1-2):10-21.

Tahvanainen J, Kyläniemi MK, Kanduri K, Gupta B, Lähteenmäki H, Kallonen T, Rajavuori A, Rasool O, Koskinen PJ, Rao KV, Lähdesmäki H, Lahesmaa R. Proviral integration site for Moloney murine leukemia virus (PIM) kinases promote human T helper 1 cell differentiation. J Biol Chem. 2013 Feb 1;288(5):3048-58.

Toivonen M, Tringham M, Kurko J, Terho P, Simell O, Heiskanen KM, Mykkänen J. Interactions of y+LAT1 and 4F2hc in the y+l amino acid transporter complex: consequences of lysinuric protein intolerance-causing mutations. Gen Physiol Biophys. 2013 Dec;32(4):479-88.

Tuomela J, Forsback S, Haavisto L, Vahlberg T, Grönroos TJ, Solin O, Haaparanta-Solin M. Enzyme inhibition of dopamine metabolism alters 6-[18F]FDOPA uptake in orthotopic pancreatic adenocarcinoma. EJNMMI Res. 2013 Mar 14;3(1):18.

Vihervaara A, Sergelius C, Vasara J, Blom MA, Elsing AN, Roos-Mattjus P, Sistonen L. Transcriptional response to stress in the dynamic chromatin environment of cycling and mitotic cells. Proc Natl Acad Sci U S A. 2013 Sep 3;110(36):E3388-97.

2012

Veikkolainen V, Naillat F, Railo A, Chi L, Manninen A, Hohenstein P, Hastie N, Vainio S, Elenius K. ErbB4 modulates tubular cell polarity and lumen diameter during kidney development. J Am Soc Nephrol. 2012 Jan;23(1):112-122.

Alanne MH, Siljamäki E, Peltonen S, Väänänen K, Windle JJ, Parada LF, Määttä JA, Peltonen J. Phenotypic characterization of transgenic mice harboring Nf1(+/-) or Nf1(-/-) osteoclasts in otherwise Nf1(+/+) background. J Cell Biochem 2012 Jun;113(6):2136-46.

Lahtinen SJ, Forssten S, Aakko J, Granlund L, Rautonen N, Salminen S, Viitanen M, Ouwehand AC. Probiotic cheese containing Lactobacillus rhamnosus HN001 and Lactobacillus acidophilus NCFM® modifies subpopulations of fecal lactobacilli and Clostridium difficile in the elderly. Age (Dordr). 2012 Feb;34(1):133-143

Närvä E, Rahkonen N, Emani MR, Lund R, Pursiheimo JP, Nästi J, Autio R, Rasool O, Denessiouk K, Lähdesmäki H, Rao A, Lahesmaa R. RNA-binding protein L1TD1 interacts with LIN28 via RNA and is required for human embryonic stem cell self-renewal and cancer cell proliferation. Stem Cells. 2012 Mar;30(3):452-460

Kukko-Lukjanov TK, Grönman M, Lintunen M, Laurén HB, Michelsen KA, Panula P, Holopainen IE. Histamine 1 receptor knock out mice show age-dependent susceptibility to status epilepticus and consequent neuronal damage. Epilepsy Res. 2012 Jun;100(1-2):80-92.

Ventelä S, Mäkelä JA, Kulmala J, Westermarck J, Toppari J. Identification and Regulation of a Stage-Specific Stem Cell Niche Enriched by Nanog Positive Spermatogonial Stem Cells in the Mouse Testis. Stem Cells. 2012 May;30(5):1008-20.

Paatero I, Jokilammi A, Heikkinen PT, Iljin K, Kallioniemi OP, Jones FE, Jaakkola PM, Elenius K. Interaction with ErbB4 Promotes Hypoxia-inducible Factor-1α Signaling. J Biol Chem. 2012 Mar;287(13):9659-9671.

Korhonen JT, Puolakkainen M, Häivälä R, Penttilä T, Haveri A, Markkula E, Lahesmaa R. Flotillin-1 (Reggie-2) contributes to Chlamydia pneumoniae growth and is associated with bacterial inclusion. Infect Immun. 2012 Mar;80(3):1072-1078.

Koskinen A, Lukkarinen H, Moritz N, Aho H, Kääpä P, Soukka H. Fetal hyperglycemia alters lung structural development in neonatal rat. Pediatr Pulmonol 2012 Mar;47(3):275-282.

Korhonen JT, Puolakkainen M, Haveri A, Tammiruusu A, Sarvas M, Lahesmaa R. Chlamydia pneumoniae entry into epithelial cells by clathrin-independent endocytosis. Microb Pathog. 2012 Mar;52(3):157-164.

Närvä E, Rahkonen N, Emani MR, Lund R, Pursiheimo JP, Nästi J, Autio R, Rasool O, Denessiouk K, Lähdesmäki H, Rao A, Lahesmaa R. RNA-binding protein L1TD1 interacts with LIN28 via RNA and is required for human embryonic stem cell self-renewal and cancer cell proliferation. Stem Cells 2012 Mar;30(3):452-460.

Ruuska M, Sahlberg AS, Colbert RA, Granfors K, Penttinen MA. Enhanced phosphorylation of STAT-1 is dependent on double-stranded RNA-dependent protein kinase signaling in HLA-B27-expressing U937 monocytic cells. Arthritis Rheum. 2012 Mar;64(3):772-777.

Salmela AL, Pouwels J, Kukkonen-Macchi A, Waris S, Toivonen P, Jaakkola K, Mäki-Jouppila J, Kallio L, Kallio MJ. The flavonoid eupatorin inactivates the mitotic checkpoint leading to polyploidy and apoptosis. Exp Cell Res. 2012 Mar;318(5):578-592.

Arjonen A, Alanko J, Veltel S, Ivaska J. Distinct Recycling of Active and Inactive β1 Integrins. Traffic. 2012 Apr;13(4):610-25.
Kankaanpää P, Paavolainen L, Tiitta S, Karjalainen M, Päivärinne J, Nieminen J, Marjomäki V, Heino J, White DJ. BioImageXD: an open, general-purpose and high-throughput image-processing platform. Nat Methods. 2012 28;9(7):683-9.

Mrówczyńska L, Lindqvist C, Iglič A, Hägerstrand H. Spontaneous curvature of ganglioside GM1–effect of cross-linking. Biochem Biophys Res Commun. 2012 Jun;15;422(4):776-9.

Karaman DS, Desai D, Senthilkumar R, Johansson EM, Råtts N, Odén M, Eriksson JE, Sahlgren C, Toivola DM, Rosenholm JM. Shape engineering vs organic modification of inorganic nanoparticles as a tool for enhancing cellular internalization. Nanoscale Res Lett. 2012 Jul;1;7(1):358.

Björkblom B, Padzik A, Mohammad H, Westerlund N, Komulainen E, Hollos P, Parviainen L, Papageorgiou AC, Iljin K, Kallioniemi O, Kallajoki M,Courtney MJ, Mågård M, James P, Coffey ET. c-Jun N-terminal kinase phosphorylation of MARCKSL1 determines actin stability and migration in neurons and in cancer cells. Mol Cell Biol. 2012 Sep;32(17):3513-26.

Asghar MYViitanen TKemppainen KTörnquist K. Sphingosine 1-phosphate and human ether-a’-go-go-related gene potassium channels modulate migration in human anaplastic thyroid cancer cells. Endocr Relat Cancer. 2012 Sep 21;19(5):667-80.

Skogman ME, Vuorela PM, Fallarero A. Combining biofilm matrix measurements with biomass and viability assays in susceptibility assessments of antimicrobials against Staphylococcus aureus biofilms. J Antibiot (Tokyo). 2012 Sep;65(9):453-9.

Skogman MEKujala JBusygin ILeinob RVuorela PMFallarero A. Evaluation of antibacterial and anti-biofilm activities of cinchona alkaloid derivatives against Staphylococcus aureus. Nat Prod Commun. 2012 Sep;7(9):1173-6.

Vesterkvist PS, Misiorek JO, Spoof LE, Toivola DM, Meriluoto JA. Comparative cellular toxicity of hydrophilic and hydrophobic microcystins on Caco-2 cells. Toxins. 2012 Oct; 4(11):1008-1023.

Sukumaran P, Löf C, Kemppainen K, Kankaanpää P, Pulli I, Näsman J, Viitanen T, Törnquist K. Canonical Transient Receptor Potential Channel 2 (TRPC2) as a Major Regulator of Calcium Homeostasis in Rat Thyroid FRTL-5 Cells: importance of protein kinase C δ (PKCδ) and stromal interaction molecule 2 (STIM2). J Biol Chem. 2012 Dec; 28;287(53):44345-60.

Löf C, Sukumaran P, Viitanen T, Vainio M, Kemppainen K, Pulli I, Näsman J, Kukkonen JP, Törnquist K. Communication between the calcium and cAMP pathways regulate the expression of the TSH receptor: TRPC2 in the center of action. Mol Endocrinol. 2012 Dec;26(12):2046-57.

Ferraris SE, Isoniemi K, Torvaldson E, Anckar J, Westermarck J, Eriksson JE. Nucleolar AATF regulates c-Jun-mediated apoptosis. Mol Biol Cell. 2012 Nov;23(21):4323-32.

Algars A, Irjala H, Vaittinen S, Huhtinen H, Sundström J, Salmi M, Ristamäki R, Jalkanen S. Type and location of tumor-infiltrating macrophages and lymphatic vessels predict survival of colorectal cancer patients. Int J Cancer 2012 Aug 15;131(4):864-73.

2011

Björkbom A, Róg T, Kankaanpää P, Lindroos D, Kaszuba K, Kurita M, Yamaguchi S, Yamamoto T, Jaikishan S, Paavolainen L, Päivärinne J, Nyholm TK, Katsumura S, Vattulainen I, Slotte JP. N- and O-methylation of sphingomyelin markedly affects its membrane properties and interactions with cholesterol. Biochim Biophys Acta. 2011 Apr;1808(4):1179-86.

Peri P, Nuutila K, Vuorinen T, Saukko P, Hukkanen V: Cathepsins are involved in virus-induced cell death in ICP4 and Us3 deletion mutant herpes simplex virus type 1-infected monocytic cells. J Gen Virol. 2011 Jan;92(Pt 1):173-180.

Heikkilä O, Kainulainen M, Susi P: A combined method for rescue of modified enteroviruses by mutagenic primers, long PCR and T7 RNA polymerase-driven in vivo transcription. J Virol Methods 2011 Jan;171(1):129-133.

Jouhilahti EM, Peltonen S, Callens T, Jokinen E, Heape AM, Messiaen L, Peltonen J: The development of cutaneous neurofibromas. Am J Pathol. 2011 Feb;178(2):500-505.

Toivonen HT, Meinander A, Asaoka T, Westerlund M, Pettersson F, Mikhailov A, Eriksson JE, Saxén H. Modeling reveals that dynamic regulation of c-FLIP levels determines cell-to-cell distribution of CD95-mediated apoptosis. J Biol Chem. 2011 May 27;286(21):18375-82.
Högel H, Rantanen K, Jokilehto T, Grenman R, Jaakkola PM. Prolyl hydroxylase PHD3 enhances the hypoxic survival and G1 to S transition of carcinoma cells. PLoS ONE 2011 6(11):e27112-e27112.

Korhonen HM, Meikar O, Yadav RP, Papaioannou MD, Romero Y, Da Ros M, Herrera PL, Toppari J, Nef S, Kotaja N. Dicer is required for haploid male germ cell differentiation in mice. PLoS ONE 2011 6(9):e24821-e24821.

Laatikainen LE, Incoronato M, Castellone MD, Laurila JP, Santoro M, Laukkanen MO. SOD3 decreases ischemic injury derived apoptosis through phosphorylation of Erk1/2, Akt, and FoxO3a. PLoS ONE 2011 6(8):e24456-e24456.

Högel H, Rantanen K, Jokilehto T, Grenman R, Jaakkola PM. Prolyl hydroxylase PHD3 enhances the hypoxic survival and G1 to S transition of carcinoma cells. PLoS ONE 2011 6(11):e27112-e27112.

Landor SK, Mutvei AP, Mamaeva V, Jin S, Busk M, Borra R, Grönroos TJ, Kronqvist P, Lendahl U, Sahlgren CM. Hypo- and hyperactivated Notch signaling induce a glycolytic switch through distinct mechanisms. Proc Natl Acad Sci USA. 2011 Nov;108(46):18814-18819.

Ålgars A, Karikoski M, Yegutkin GG, Stoitzner P, Niemelä J, Salmi M, Jalkanen S. Different role of CD73 in leukocyte trafficking via blood and lymph vessels. Blood. 2011 Apr;117(16):4387-4393.

Pallari HM, Lindqvist J, Torvaldson E, Ferraris SE, He T, Sahlgren C, Eriksson JE. Nestin as a regulator of Cdk5 in differentiating myoblasts. Mol Biol Cell. 2011 May;22(9):1539-1549.

Hänninen A, Maksimow M, Alam C, Morgan DJ, Jalkanen S. Ly6C supports preferential homing of central memory CD8+ T cells into lymph nodes. Eur J Immunol. 2011 Mar;41(3):634-644.

Westerlund N, Zdrojewska J, Padzik A, Komulainen E, Björkblom B, Rannikko E, Tararuk T, Garcia-Frigola C, Sandholm J, Nguyen L, Kallunki T, Courtney MJ, Coffey ET. Phosphorylation of SCG10/stathmin-2 determines multipolar stage exit and neuronal migration rate. Nat Neurosci. 2011 Mar;14(3):305-313.

Heinonen J, Taipaleenmäki H, Roering P, Takatalo M, Harkness L, Sandholm J, Uusitalo-Järvinen H, Kassem M, Kiviranta I, Laitala-Leinonen T, Säämänen AM. Snorc is a novel cartilage specific small membrane proteoglycan expressed in differentiating and articular chondrocytes. Osteoarthr Cartil. 2011 Aug;19(8):1026-1035.

Mohseni P, Sung HK, Murphy AJ, Laliberte CL, Pallari HM, Henkelman M, Georgiou J, Xie G, Quaggin SE, Thorner PS, Eriksson JE, Nagy A. Nestin is not essential for development of the CNS but required for dispersion of acetylcholine receptor clusters at the area of neuromuscular junctions. J Neurosci. 2011 Aug;31(32):11547-11552.

Sahlberg AS, Ruuska M, Colbert RA, Granfors K, Penttinen MA. Altered PKR signalling and C/EBPβ expression is associated with HLA-B27 expression in monocytic cells. Scand J Immunol. 2011 Oct 11.

Asaoka T, Kaunisto A, Eriksson JE. Regulation of cell death by c-FLIP phosphorylation. Adv Exp Med Biol. 2011;691:625-30.

Korhonen HM, Meikar O, Yadav RP, Papaioannou MD, Romero Y, Da Ros M, Herrera PL, Toppari J, Nef S, Kotaja N. Dicer is required for haploid male germ cell differentiation in mice. PLoS ONE. 2011 6(9):e24821-e24821.

Hakkila KM, Nikander PA, Junttila SM, Lamminmäki UJ, Virta MP. Cd-specific mutants of mercury-sensing regulatory protein MerR, generated by directed evolution. Appl Environ Microbiol. 2011 Sep;77(17):6215-6224.

Kakko T, Jaakkola U, Raitakari OT, Kallio J. Inflammatory effects of blood leukocytes: association with vascular function in neuropeptide Y proline 7-genotyped type 2 diabetes patients. Diab Vasc Dis Res. 2011 Jul;8(3):221-228.

Alinikula J, Nera KP, Junttila S, Lassila O. Alternate pathways for Bcl6-mediated regulation of B cell to plasma cell differentiation. Eur J Immunol. 2011 Aug;41(8):2404-2413.

Rajasärkkä J, Hakkila K, Virta M. Developing a compound-specific receptor for bisphenol A by directed evolution of human estrogen receptor α. Biotechnol Bioeng. 2011 Nov;108(11):2526-2534.

Mrówczyńska L, Bobrowska-Hägerstrand M, Hägerstrand H, Lindqvist C. Increased sensitivity of cholera toxin B treated K562 cells to natural killer cells. Cell Immunol. 2011 269(1):1-4.

Palani S, Maksimow M, Miiluniemi M, Auvinen K, Jalkanen S, Salmi M. Stabilin-1/CLEVER-1, a type 2 macrophage marker, is an adhesion and scavenging molecule on human placental macrophages. Eur J Immunol. 2011 Jul;41(7):2052-2063.

Yegutkin GG, Marttila-Ichihara F, Karikoski M, Niemelä J, Laurila JP, Elima K, Jalkanen S, Salmi M. Altered purinergic signaling in CD73-deficient mice inhibits tumor progression. Eur J Immunol. 2011 May;41(5):1231-1241.

Alam C, Bittoun E, Bhagwat D, Valkonen S, Saari A, Jaakkola U, Eerola E, Huovinen P, Hänninen A. Effects of a germ-free environment on gut immune regulation and diabetes progression in non-obese diabetic (NOD) mice. Diabetologia. 2011 Jun;54(6):1398-1406.

Ålgars A, Karikoski M, Yegutkin GG, Stoitzner P, Niemelä J, Salmi M, Jalkanen S. Different role of CD73 in leukocyte trafficking via blood and lymph vessels. Blood. 2011 Apr;117(16):4387-4393.

Hänninen A, Maksimow M, Alam C, Morgan DJ, Jalkanen S. Ly6C supports preferential homing of central memory CD8+ T cells into lymph nodes. Eur J Immunol. 2011 Mar;41(3):634-644.

Järvelä JT, Ruohonen S, Kukko-Lukjanov TK, Plysjuk A, Lopez-Picon FR, Holopainen IE. Kainic acid-induced neurodegeneration and activation of inflammatory processes in organotypic hippocampal slice cultures: treatment with cyclooxygenase-2 inhibitor does not prevent neuronal death. Neuropharmacology. 2011 Jun;60(7-8):1116-1125.

Trotta A, Wrzaczek M, Scharte J, Tikkanen M, Konert G, Rahikainen M, Holmström M, Hiltunen HM, Rips S, Sipari N, Mulo P, Weis E, von Schaewen A, Aro EM, Kangasjärvi S. Regulatory subunit B’gamma of protein phosphatase 2A prevents unnecessary defense reactions under low light in Arabidopsis. Plant Physiol. 2011 Jul;156(3):1464-1480.

Salo J, Loimaranta V, Lahdenne P, Viljanen MK, Hytönen J. Decorin binding by DbpA and B of Borrelia garinii, Borrelia afzelii, and Borrelia burgdorferi sensu Stricto. J Infect Dis. 2011 Jul;204(1):65-73.

Kuokkanen E, Riise Stensland HM, Smith W, Kjeldsen Buvang E, Van Nguyen L, Nilssen Ø, Heikinheimo P. Molecular and cellular characterization of novel {alpha}-mannosidosis mutations. Hum Mol Genet. 2011 Jul;20(13):2651-2661.

Kukkonen-Macchi A, Sicora O, Kaczynska K, Oetken-Lindholm C, Pouwels J, Laine L, Kallio MJ. Loss of p38gamma MAPK induces pleiotropic mitotic defects and massive cell death. J Cell Sci. 2011 Jan;124(Pt 2):216-227.

Mamaeva V, Rosenholm JM, Bate-Eya LT, Bergman L, Peuhu E, Duchanoy A, Fortelius LE, Landor S, Toivola DM, Lindén M, Sahlgren C. Mesoporous silica nanoparticles as drug delivery systems for targeted inhibition of Notch signaling in cancer. Mol Ther. 2011 Aug;19(8):1538-1546.

Veikkolainen V, Vaparanta K, Halkilahti K, Iljin K, Sundvall M, Elenius K. Function of ERBB4 is determined by alternative splicing. Cell Cycle. 2011 Aug;10(16):2647-2657.

Aalto K, Autio A, Kiss EA, Elima K, Nymalm Y, Veres TZ, Marttila-Ichihara F, Elovaara H, Saanijoki T, Crocker PR, Maksimow M, Bligt E, Salminen TA, Salmi M, Roivainen A, Jalkanen S. Siglec-9 is a novel leukocyte ligand for vascular adhesion protein-1 and can be used in PET imaging of inflammation and cancer. Blood. 2011 Sep;118(13):3725-3733.

Knaapi J, Lukkarinen H, Kiviranta R, Vuorio E, Kääpä P. Cathepsin K deficiency aggravates lung injury in hyperoxia-exposed newborn mice. Exp Lung Res. 2011 Sep;37(7):408-418.

Hou M, Stukenborg JB, Nurmio M, Andersson M, Toppari J, Söder O, Jahnukainen K. Ontogenesis of Ap-2γ expression in rat testes. Sex Dev 2011 5(4):188-196.

Nermes M, Kantele JM, Atosuo TJ, Salminen S, Isolauri E. Interaction of orally administered Lactobacillus rhamnosus GG with skin and gut microbiota and humoral immunity in infants with atopic dermatitis. Clin Exp Allergy 2011 Mar;41(3):370-377.

Pihlaja R, Koistinaho J, Kauppinen R, Sandholm J, Tanila H, Koistinaho M. Multiple cellular and molecular mechanisms are involved in human Aβ clearance by transplanted adult astrocytes. Glia. 2011 Nov;59(11):1643-1657.