2011

Björkbom A, Róg T, Kankaanpää P, Lindroos D, Kaszuba K, Kurita M, Yamaguchi S, Yamamoto T, Jaikishan S, Paavolainen L, Päivärinne J, Nyholm TK, Katsumura S, Vattulainen I, Slotte JP. N- and O-methylation of sphingomyelin markedly affects its membrane properties and interactions with cholesterol. Biochim Biophys Acta. 2011 Apr;1808(4):1179-86.

Peri P, Nuutila K, Vuorinen T, Saukko P, Hukkanen V: Cathepsins are involved in virus-induced cell death in ICP4 and Us3 deletion mutant herpes simplex virus type 1-infected monocytic cells. J Gen Virol. 2011 Jan;92(Pt 1):173-180.

Heikkilä O, Kainulainen M, Susi P: A combined method for rescue of modified enteroviruses by mutagenic primers, long PCR and T7 RNA polymerase-driven in vivo transcription. J Virol Methods 2011 Jan;171(1):129-133.

Jouhilahti EM, Peltonen S, Callens T, Jokinen E, Heape AM, Messiaen L, Peltonen J: The development of cutaneous neurofibromas. Am J Pathol. 2011 Feb;178(2):500-505.

Toivonen HT, Meinander A, Asaoka T, Westerlund M, Pettersson F, Mikhailov A, Eriksson JE, Saxén H. Modeling reveals that dynamic regulation of c-FLIP levels determines cell-to-cell distribution of CD95-mediated apoptosis. J Biol Chem. 2011 May 27;286(21):18375-82.

Högel H, Rantanen K, Jokilehto T, Grenman R, Jaakkola PM. Prolyl hydroxylase PHD3 enhances the hypoxic survival and G1 to S transition of carcinoma cells. PLoS ONE 2011 6(11):e27112-e27112.

Korhonen HM, Meikar O, Yadav RP, Papaioannou MD, Romero Y, Da Ros M, Herrera PL, Toppari J, Nef S, Kotaja N. Dicer is required for haploid male germ cell differentiation in mice. PLoS ONE 2011 6(9):e24821-e24821.

Laatikainen LE, Incoronato M, Castellone MD, Laurila JP, Santoro M, Laukkanen MO. SOD3 decreases ischemic injury derived apoptosis through phosphorylation of Erk1/2, Akt, and FoxO3a. PLoS ONE 2011 6(8):e24456-e24456.

Högel H, Rantanen K, Jokilehto T, Grenman R, Jaakkola PM. Prolyl hydroxylase PHD3 enhances the hypoxic survival and G1 to S transition of carcinoma cells. PLoS ONE 2011 6(11):e27112-e27112.

Landor SK, Mutvei AP, Mamaeva V, Jin S, Busk M, Borra R, Grönroos TJ, Kronqvist P, Lendahl U, Sahlgren CM. Hypo- and hyperactivated Notch signaling induce a glycolytic switch through distinct mechanisms. Proc Natl Acad Sci USA. 2011 Nov;108(46):18814-18819.

Ålgars A, Karikoski M, Yegutkin GG, Stoitzner P, Niemelä J, Salmi M, Jalkanen S. Different role of CD73 in leukocyte trafficking via blood and lymph vessels. Blood. 2011 Apr;117(16):4387-4393.

Pallari HM, Lindqvist J, Torvaldson E, Ferraris SE, He T, Sahlgren C, Eriksson JE. Nestin as a regulator of Cdk5 in differentiating myoblasts. Mol Biol Cell. 2011 May;22(9):1539-1549.

Hänninen A, Maksimow M, Alam C, Morgan DJ, Jalkanen S. Ly6C supports preferential homing of central memory CD8+ T cells into lymph nodes. Eur J Immunol. 2011 Mar;41(3):634-644.

Westerlund N, Zdrojewska J, Padzik A, Komulainen E, Björkblom B, Rannikko E, Tararuk T, Garcia-Frigola C, Sandholm J, Nguyen L, Kallunki T, Courtney MJ, Coffey ET. Phosphorylation of SCG10/stathmin-2 determines multipolar stage exit and neuronal migration rate. Nat Neurosci. 2011 Mar;14(3):305-313.

Heinonen J, Taipaleenmäki H, Roering P, Takatalo M, Harkness L, Sandholm J, Uusitalo-Järvinen H, Kassem M, Kiviranta I, Laitala-Leinonen T, Säämänen AM. Snorc is a novel cartilage specific small membrane proteoglycan expressed in differentiating and articular chondrocytes. Osteoarthr Cartil. 2011 Aug;19(8):1026-1035.

Mohseni P, Sung HK, Murphy AJ, Laliberte CL, Pallari HM, Henkelman M, Georgiou J, Xie G, Quaggin SE, Thorner PS, Eriksson JE, Nagy A. Nestin is not essential for development of the CNS but required for dispersion of acetylcholine receptor clusters at the area of neuromuscular junctions. J Neurosci. 2011 Aug;31(32):11547-11552.

Sahlberg AS, Ruuska M, Colbert RA, Granfors K, Penttinen MA. Altered PKR signalling and C/EBPβ expression is associated with HLA-B27 expression in monocytic cells. Scand J Immunol. 2011 Oct 11.

Asaoka T, Kaunisto A, Eriksson JE. Regulation of cell death by c-FLIP phosphorylation. Adv Exp Med Biol. 2011;691:625-30.
Korhonen HM, Meikar O, Yadav RP, Papaioannou MD, Romero Y, Da Ros M, Herrera PL, Toppari J, Nef S, Kotaja N. Dicer is required for haploid male germ cell differentiation in mice. PLoS ONE. 2011 6(9):e24821-e24821.

Hakkila KM, Nikander PA, Junttila SM, Lamminmäki UJ, Virta MP. Cd-specific mutants of mercury-sensing regulatory protein MerR, generated by directed evolution. Appl Environ Microbiol. 2011 Sep;77(17):6215-6224.

Kakko T, Jaakkola U, Raitakari OT, Kallio J. Inflammatory effects of blood leukocytes: association with vascular function in neuropeptide Y proline 7-genotyped type 2 diabetes patients. Diab Vasc Dis Res. 2011 Jul;8(3):221-228.

Alinikula J, Nera KP, Junttila S, Lassila O. Alternate pathways for Bcl6-mediated regulation of B cell to plasma cell differentiation. Eur J Immunol. 2011 Aug;41(8):2404-2413.

Rajasärkkä J, Hakkila K, Virta M. Developing a compound-specific receptor for bisphenol A by directed evolution of human estrogen receptor α. Biotechnol Bioeng. 2011 Nov;108(11):2526-2534.

Mrówczyńska L, Bobrowska-Hägerstrand M, Hägerstrand H, Lindqvist C. Increased sensitivity of cholera toxin B treated K562 cells to natural killer cells. Cell Immunol. 2011 269(1):1-4.

Palani S, Maksimow M, Miiluniemi M, Auvinen K, Jalkanen S, Salmi M. Stabilin-1/CLEVER-1, a type 2 macrophage marker, is an adhesion and scavenging molecule on human placental macrophages. Eur J Immunol. 2011 Jul;41(7):2052-2063.

Yegutkin GG, Marttila-Ichihara F, Karikoski M, Niemelä J, Laurila JP, Elima K, Jalkanen S, Salmi M. Altered purinergic signaling in CD73-deficient mice inhibits tumor progression. Eur J Immunol. 2011 May;41(5):1231-1241.

Alam C, Bittoun E, Bhagwat D, Valkonen S, Saari A, Jaakkola U, Eerola E, Huovinen P, Hänninen A. Effects of a germ-free environment on gut immune regulation and diabetes progression in non-obese diabetic (NOD) mice. Diabetologia. 2011 Jun;54(6):1398-1406.

Ålgars A, Karikoski M, Yegutkin GG, Stoitzner P, Niemelä J, Salmi M, Jalkanen S. Different role of CD73 in leukocyte trafficking via blood and lymph vessels. Blood. 2011 Apr;117(16):4387-4393.

Hänninen A, Maksimow M, Alam C, Morgan DJ, Jalkanen S. Ly6C supports preferential homing of central memory CD8+ T cells into lymph nodes. Eur J Immunol. 2011 Mar;41(3):634-644.

Järvelä JT, Ruohonen S, Kukko-Lukjanov TK, Plysjuk A, Lopez-Picon FR, Holopainen IE. Kainic acid-induced neurodegeneration and activation of inflammatory processes in organotypic hippocampal slice cultures: treatment with cyclooxygenase-2 inhibitor does not prevent neuronal death. Neuropharmacology. 2011 Jun;60(7-8):1116-1125.

Trotta A, Wrzaczek M, Scharte J, Tikkanen M, Konert G, Rahikainen M, Holmström M, Hiltunen HM, Rips S, Sipari N, Mulo P, Weis E, von Schaewen A, Aro EM, Kangasjärvi S. Regulatory subunit B’gamma of protein phosphatase 2A prevents unnecessary defense reactions under low light in Arabidopsis. Plant Physiol. 2011 Jul;156(3):1464-1480.

Salo J, Loimaranta V, Lahdenne P, Viljanen MK, Hytönen J. Decorin binding by DbpA and B of Borrelia garinii, Borrelia afzelii, and Borrelia burgdorferi sensu Stricto. J Infect Dis. 2011 Jul;204(1):65-73.

Kuokkanen E, Riise Stensland HM, Smith W, Kjeldsen Buvang E, Van Nguyen L, Nilssen Ø, Heikinheimo P. Molecular and cellular characterization of novel {alpha}-mannosidosis mutations. Hum Mol Genet. 2011 Jul;20(13):2651-2661.

Kukkonen-Macchi A, Sicora O, Kaczynska K, Oetken-Lindholm C, Pouwels J, Laine L, Kallio MJ. Loss of p38gamma MAPK induces pleiotropic mitotic defects and massive cell death. J Cell Sci. 2011 Jan;124(Pt 2):216-227.

Mamaeva V, Rosenholm JM, Bate-Eya LT, Bergman L, Peuhu E, Duchanoy A, Fortelius LE, Landor S, Toivola DM, Lindén M, Sahlgren C. Mesoporous silica nanoparticles as drug delivery systems for targeted inhibition of Notch signaling in cancer. Mol Ther. 2011 Aug;19(8):1538-1546.

Veikkolainen V, Vaparanta K, Halkilahti K, Iljin K, Sundvall M, Elenius K. Function of ERBB4 is determined by alternative splicing. Cell Cycle. 2011 Aug;10(16):2647-2657.

Aalto K, Autio A, Kiss EA, Elima K, Nymalm Y, Veres TZ, Marttila-Ichihara F, Elovaara H, Saanijoki T, Crocker PR, Maksimow M, Bligt E, Salminen TA, Salmi M, Roivainen A, Jalkanen S. Siglec-9 is a novel leukocyte ligand for vascular adhesion protein-1 and can be used in PET imaging of inflammation and cancer. Blood. 2011 Sep;118(13):3725-3733.

Knaapi J, Lukkarinen H, Kiviranta R, Vuorio E, Kääpä P. Cathepsin K deficiency aggravates lung injury in hyperoxia-exposed newborn mice. Exp Lung Res. 2011 Sep;37(7):408-418.

Hou M, Stukenborg JB, Nurmio M, Andersson M, Toppari J, Söder O, Jahnukainen K. Ontogenesis of Ap-2γ expression in rat testes. Sex Dev 2011 5(4):188-196.

Nermes M, Kantele JM, Atosuo TJ, Salminen S, Isolauri E. Interaction of orally administered Lactobacillus rhamnosus GG with skin and gut microbiota and humoral immunity in infants with atopic dermatitis. Clin Exp Allergy 2011 Mar;41(3):370-377.

Pihlaja R, Koistinaho J, Kauppinen R, Sandholm J, Tanila H, Koistinaho M. Multiple cellular and molecular mechanisms are involved in human Aβ clearance by transplanted adult astrocytes. Glia. 2011 Nov;59(11):1643-1657.