2013

Alam CM, Silvander JS, Daniel EN, Tao GZ, Kvarnström SM, Alam P, Omary MB, Hänninen A, Toivola DM. Keratin 8 modulates β-cell stress responses and normoglycaemia. J Cell Sci. 2013 Dec 15;126(Pt 24):5635-44.

Arjonen A, Kaukonen R, Mattila E, Rouhi P, Högnäs G, Sihto H, Miller BW, Morton JP, Bucher E, Taimen P, Virtakoivu R, Cao Y, Sansom OJ, Joensuu H,
Ivaska J. Mutant p53-associated myosin-X upregulation promotes breast cancer invasion and metastasis. J Clin Invest. 2014 Mar;124(3):1069-82.

Autio A, Vainio PJ, Suilamo S, Mali A, Vainio J, Saanijoki T, Noponen T, Ahtinen H, Luoto P, Teräs M, Jalkanen S, Roivainen A. Preclinical evaluation of a radioiodinated fully human antibody for in vivo imaging of vascular adhesion protein-1-positive vasculature in inflammation. J Nucl Med. 2013 Aug;54(8):1315-9

Bergman L, Kankaanpää P, Tiitta S, Duchanoy A, Li L, Heino J, Lindén M. Intracellular degradation of multilabeled poly(ethylene imine)-mesoporous silica-silica nanoparticles: implications for drug release. Mol Pharm. 2013 May 6;10(5):1795-803.

Castellone MD, Laatikainen LE, Laurila JP, Langella A, Hematti P, Soricelli A, Salvatore M, Laukkanen MO. Brief report: Mesenchymal stromal cell atrophy in coculture increases aggressiveness of transformed cells. Stem Cells. 2013 Jun;31(6):1218-23.

Eerola K, Nordlund W, Virtanen S, Dickens AM, Mattila M, Ruohonen ST, Chua SC Jr, Wardlaw SL,Savontaus M, Savontaus E. Lentivirus-Mediated α-Melanocyte-Stimulating Hormone Overexpression in the Hypothalamus Decreases Diet Induced Obesity in Mice. J Neuroendocrinol. 2013 Dec;25(12):1298-307.

Ermakova M, Battchikova N, Allahverdiyeva Y, Aro EM. Novel heterocyst-specific flavodiiron proteins in Anabaena sp. PCC 7120. FEBS Lett. 2013 Jan 4;587(1):82-7.

Emani R, Asghar MN, Toivonen R, Lauren L, Söderström M, Toivola DM, van Tol EA, Hänninen A. Casein hydrolysate diet controls intestinal T cell activation, free radical production and microbial colonisation in NOD mice. Diabetologia. 2013 Aug;56(8):1781-91.

Fallarero A, Skogman M, Kujala J, Rajaratnam M, Moreira VM, Yli-Kauhaluoma J, Vuorela P. (+)-Dehydroabietic Acid, an Abietane-Type Diterpene, Inhibits Staphylococcus aureus Biofilms in Vitro. Int J Mol Sci. 2013 Jun 5;14(6):12054-72.

Gardberg M, Kaipio K, Lehtinen L, Mikkonen P, Heuser VD, Talvinen K, Iljin K, Kampf C, Uhlen M, Grénman R, Koivisto M, Carpén O. FHOD1, a formin upregulated in epithelial-mesenchymal transition, participates in cancer cell migration and invasion. PLoS One. 2013 Sep 26;8(9):e74923.

Hirvonen MJ, Büki KG, Sun Y, Mulari MT, Härkönen PL, Väänänen KH. Novel interaction of Rab13 and Rab8 with endospanins. FEBS Open Bio. 2013 Jan 22;3:83-8.

Hämälistö S, Pouwels J, de Franceschi N, Saari M, Ivarsson Y, Zimmermann P, Brech A, Stenmark H, Ivaska J.  A ZO-1/α5β1-integrin complex regulates cytokinesis downstream of PKCε in NCI-H460 cells plated on fibronectin. PLoS One. 2013 Aug 13;8(8):e70696.

Jääskeläinen AE, Seppälä S, Kakko T, Jaakkola U, Kallio J. Systemic treatment with neuropeptide Y receptor Y1-antagonist enhances atherosclerosis and stimulates IL-12 expression in ApoE deficient mice. Neuropeptides. 2013 Apr;47(2):67-73.

Kaitaniemi S, Grön K, Elovaara H, Salmi M, Jalkanen S, Elima K. Functional modulation of vascular adhesion protein-1 by a novel splice variant. PLoS One. 2013;8(1):e54151.

Kalliokoski T1, Tuomela J, Haavisto L, Forsback S, Snellman A, Helin S, Grönroos TJ, Solin O, Haaparanta-Solin M. 6-[18F]fluoro-L-DOPA uptake in the rat pancreas is dependent on the tracer metabolism.  Mol Imaging Biol. 2014 Jun;16(3):403-11.

Keuschnigg J, Karinen S, Auvinen K, Irjala H, Mpindi JP, Kallioniemi O, Hautaniemi S, Jalkanen S, Salmi M. Plasticity of blood- and lymphatic endothelial cells and marker identification. PLoS One.2013 Sep 10;8(9):e74293.

Kiriazis A, Vahakoski RL, Santio NM, Arnaudova R, Eerola SK, Rainio EM, Aumüller IB, Yli-Kauhaluoma J, Koskinen PJ.Tricyclic Benzo[cd]azulenes selectively inhibit activities of Pim kinases and restrict growth of Epstein-Barr virus-transformed cells. PLoS One. 2013;8(2):e55409.

Korhonen JT, Olkkonen VM, Lahesmaa R, Puolakkainen M. ABC-cassette transporter 1 (ABCA1) expression in epithelial cells in Chlamydia pneumoniae infection. Microb Pathog. 2013 Aug-Sep;61-62:57-61.

Laine A, Sihto H, Come C, Rosenfeldt MT, Zwolinska A, Niemelä M, Khanna A, Chan EK, Kähäri VM, Kellokumpu-Lehtinen PL, Sansom OJ, Evan GI, Junttila MR, Ryan KM,

Marine JC, Joensuu H, Westermarck J. Senescence sensitivity of breast cancer cells is defined by positive feedback loop between CIP2A and E2F1. Cancer Discov. 2013 Feb;3(2):182-97.

Laurén HB, Ruohonen S, Kukko-Lukjanov TK, Virta JE, Grönman M, Lopez-Picon FR, Järvelä JT, Holopainen IE. Status epilepticus alters neurogenesis and decreases the number of GABAergic neurons in the septal dentate gyrus of 9-day-old rats at the early phase of epileptogenesis. Brain Res. 2013 Jun 21;1516:33-44.

Najumudeen AK, Köhnke M, Solman M, Alexandrov K, Abankwa D. Cellular FRET-Biosensors to Detect Membrane Targeting Inhibitors of N-Myristoylated Proteins. PLoS One. 2013 Jun 18;8(6):e66425.

Nygårdas M, Paavilainen H, Müther N, Nagel CH, Röyttä M, Sodeik B, Hukkanen V. A herpes simplex virus-derived replicative vector expressing LIF limits experimental demyelinating disease and modulates autoimmunity. PLoS One. 2013 May 20;8(5):e64200.

Närvä E, Pursiheimo JP, Laiho A, Rahkonen N, Emani MR, Viitala M, Laurila K, Sahla R, Lund R, Lähdesmäki H, Jaakkola P, Lahesmaa R. Continuous hypoxic culturing of human embryonic stem cells enhances SSEA-3 and MYC levels. PLoS One.2013 Nov 13;8(11):e78847.

Peuhu E, Paul P, Remes M, Holmbom T, Eklund P, Sjöholm R, Eriksson JE. The antitumor lignan Nortrachelogenin sensitizes prostate cancer cells to TRAIL-induced cell death by inhibition of the Akt pathway and growth factor signaling. Biochem Pharmacol. 2013 Sep 1;86(5):571-83.

Pouwels J, De Franceschi N, Rantakari P, Auvinen K, Karikoski M, Mattila E, Potter C, Sundberg JP, Hogg N, Gahmberg CG, Salmi M, Ivaska J. SHARPIN regulates uropod detachment in migrating lymphocytes. Cell Rep. 2013 Nov 14;5(3):619-28.

Prabhakar N, Näreoja T, von Haartman E, Karaman DŞ, Jiang H, Koho S, Dolenko TA, Hänninen PE, Vlasov DI, Ralchenko VG, Hosomi S, Vlasov II, Sahlgren C, Rosenholm JM. Core-shell designs of photoluminescent nanodiamonds with porous silica coatings for bioimaging and drug delivery II: application. Nanoscale. 2013 May 7;5(9):3713-22.

Rantanen K, Pursiheimo JP, Högel H, Miikkulainen P, Sundström J, Jaakkola PM. p62/SQSTM1 regulates cellular oxygen sensing by attenuating PHD3 activity through aggregate sequestration and enhanced degradation. J Cell Sci. 2013 Mar 1;126(Pt 5):1144-54.

Ruuska M, Sahlberg AS, Granfors K, Penttinen MA. Phosphorylation of STAT-1 serine 727 is prolonged in HLA-B27-expressing human monocytic cells. PLoS One. 2013;8(1):e50684.

Sahlberg AS, Ruuska M, Granfors K, Penttinen MA. Altered Regulation of ELAVL1/HuR in HLA-B27-Expressing U937 Monocytic Cells. PLoS One. 2013 Jul 22;8(7):e70377.

Salmi M, Karikoski M, Elima K, Rantakari P, Jalkanen S. CD44 binds to macrophage mannose receptor on lymphatic endothelium and supports lymphocyte migration via afferent lymphatics. Circ Res. 2013 Jun 7;112(12):1577-82.

Sareila O, Jaakkola N, Olofsson P, Kelkka T, Holmdahl R. Identification of a region in p47phox/NCF1 crucial for phagocytic NADPH oxidase (NOX2) activation. J Leukoc  Biol. 2013 Mar;93(3):427-35.

Sukumaran P, Löf C, Pulli I, Kemppainen K, Viitanen T, Törnquist K. Significance of the transient receptor potential canonical 2 (TRPC2) channel in the regulation of rat thyroid FRTL-5 cell proliferation, migration, adhesion and invasion. Mol Cell Endocrinol. 2013 Jul 15;374(1-2):10-21.

Tahvanainen J, Kyläniemi MK, Kanduri K, Gupta B, Lähteenmäki H, Kallonen T, Rajavuori A, Rasool O, Koskinen PJ, Rao KV, Lähdesmäki H, Lahesmaa R. Proviral integration site for Moloney murine leukemia virus (PIM) kinases promote human T helper 1 cell differentiation. J Biol Chem. 2013 Feb 1;288(5):3048-58.

Toivonen M, Tringham M, Kurko J, Terho P, Simell O, Heiskanen KM, Mykkänen J. Interactions of y+LAT1 and 4F2hc in the y+l amino acid transporter complex: consequences of lysinuric protein intolerance-causing mutations. Gen Physiol Biophys. 2013 Dec;32(4):479-88.

Tuomela J, Forsback S, Haavisto L, Vahlberg T, Grönroos TJ, Solin O, Haaparanta-Solin M. Enzyme inhibition of dopamine metabolism alters 6-[18F]FDOPA uptake in orthotopic pancreatic adenocarcinoma. EJNMMI Res. 2013 Mar 14;3(1):18.

Vihervaara A, Sergelius C, Vasara J, Blom MA, Elsing AN, Roos-Mattjus P, Sistonen L. Transcriptional response to stress in the dynamic chromatin environment of cycling and mitotic cells. Proc Natl Acad Sci U S A. 2013 Sep 3;110(36):E3388-97.