2014

Alpay K, Farshchian M, Tuomela J, Sandholm J, Aittokallio K, Siljamäki E, Kallio M, Kähäri VM, Hietanen S. Inhibition of c-Abl Kinase Activity Renders Cancer Cells Highly Sensitive to Mitoxantrone. PLoS One. 2014 Aug 22;9(8):e105526.

Arjonen A, Kaukonen R, Mattila E, Rouhi P, Högnäs G, Sihto H, Miller BW, Morton JP, Bucher E, Taimen P, Virtakoivu R, Cao Y, Sansom OJ, Joensuu H, Ivaska J. Mutant p53-associated myosin-X upregulation promotes breast cancer invasion and metastasis. J Clin Invest. 2014 Mar;124(3):1069-82.

Asghar MN, Emani R, Alam C, Helenius TO, Grönroos TJ, Sareila O, Din MU, Holmdahl R, Hänninen A, Toivola DM. In vivo imaging of reactive oxygen and nitrogen species in murine colitis. Inflamm Bowel Dis. 2014 Aug;20(8):1435-47.

Auvinen K, Jalkanen S, Salmi M. Expression and function of endothelial selectins during human development.Immunology. 2014 Nov;143(3):406-15.

Böcking D, Wiltschka O, Niinimäki J, Shokry H, Brenner R, Lindén M, Sahlgren C. Mesoporous silica nanoparticle-based substrates for cell directed delivery of Notch signalling modulators to control myoblast differentiation. Nanoscale. 2014;6(3):1490-8.

Coxon FP, Joachimiak L, Najumudeen AK, Breen G, Gmach J, Oetken-Lindholm C, Way R, Dunford JE, Abankwa D, Błażewska KM. Synthesis and characterization of novel phosphonocarboxylate inhibitors of RGGT. Eur J Med Chem. 2014 Sep 12;84:77-89.

Dunkel J, Aguilar-Pimentel JA, Ollert M, Fuchs H, Gailus-Durner V, de Angelis MH, Jalkanen S, Salmi M, Veres TZ. Endothelial amine oxidase AOC3 transiently contributes to adaptive immune responses in the airways. Eur J Immunol. 2014 Nov;44(11):3232-9.

Elsing AN, Aspelin C, Björk JK, Bergman HA, Himanen SV, Kallio MJ, Roos-Mattjus P, Sistonen L..  Expression of HSF2 decreases in mitosis to enable stress-inducible transcription and cell survival. J Cell Biol. 2014 Sep 15;206(6):735-49.

Ermakova M1, Battchikova N1, Richaud P2, Leino H1, Kosourov S1, Isojärvi J1, Peltier G2, Flores E3, Cournac L2, Allahverdiyeva Y4, Aro EM4. Heterocyst-specific flavodiiron protein Flv3B enables oxic diazotrophic growth of the filamentous cyanobacterium Anabaena sp. PCC 7120. Proc Natl Acad Sci U S A. 2014 Jul 29;111(30):11205-10.

Gardberg M, Heuser VD, Iljin K, Kampf C, Uhlen M, Carpén O. Characterization of Leukocyte Formin FMNL1 Expression in Human Tissues. J Histochem Cytochem. 2014 Apr 3;62(6):460-470.

Goldgur Y, Susi P, Karelehto E, Sanmark H, Lamminmäki U, Oricchio E, Wendel HG, Nikolov DB, Himanen JP. Generation and characterization of a single-chain anti-EphA2 antibody. Growth Factors. 2014 Dec;32(6):214-22.

Gulin-Sarfraz Tina,  Jawad Sarfraz,  Didem Şen Karaman,   Jixi Zhang,   Christina Oetken-Lindholm,   Alain Duchanoy,   Jessica M. Rosenholm and   Daniel Abankwa. FRET-reporter nanoparticles to monitor redox-induced intracellular delivery of active compounds. RSC Adv., 2014,4, 16429-16437.

Guzmán C, Solman M, Abankwa D. Nanoclustering and heterogeneous membrane diffusion of Ras studied by FRAP and RICS analysis. Methods Mol Biol. 2014;1120:307-26.

Guzmán C, Bagga M, Kaur A, Westermarck J, Abankwa D. ColonyArea: an ImageJ plugin to automatically quantify colony formation in clonogenic assays. PLoS One. 2014 Mar 19;9(3):e92444.

Guzmán C, Šolman M, Ligabue A, Blaževitš O, Andrade DM, Reymond L, Eggeling C, Abankwa D. The efficacy of Raf kinase recruitment to the GTPase H-ras depends on H-ras membrane conformer-specific nanoclustering. J Biol Chem. 2014 Apr 4;289(14):9519-33.

Heinonen MT, Kanduri K, Lähdesmäki HJ, Lahesmaa R, Henttinen TA. Tubulin- and actin-associating GIMAP4 is required for IFN-γ secretion during Th cell differentiation. Immunol Cell Biol. 2014 Oct 7.

Hyder CL, Lazaro G, Pylvänäinen JW, Roberts MW, Qvarnström SM, Eriksson JE. Nestin regulates prostate cancer cell invasion by influencing the localisation and functions of FAK and integrins. J Cell Sci. 2014 May 15;127(Pt 10):2161-73.

Kalliokoski T, Tuomela J, Haavisto L, Forsback S, Snellman A, Helin S, Grönroos TJ, Solin O,Haaparanta-Solin M. 6-[18F]fluoro-L-DOPA uptake in the rat pancreas is dependent on the tracer metabolism. Mol Imaging Biol. 2014 Jun;16(3):403-11.

Karikoski M, Marttila-Ichihara F, Elima K, Rantakari P, Hollmén M, Kelkka T, Gerke H, Huovinen V, Irjala H, Holmdahl R, Salmi M, Jalkanen S. Clever-1/stabilin-1 controls cancer growth and metastasis. Clin Cancer Res. 2014 Dec 15;20(24):6452-64.

Kochin V, Shimi T, Torvaldson E, Adam SA, Goldman A, Pack CG, Melo-Cardenas J, Imanishi SY, Goldman RD, Eriksson JE. Interphase phosphorylation of lamin A. J Cell Sci. 2014 Jun 15;127(Pt 12):2683-96.

Komulainen E, Zdrojewska J, Freemantle E, Mohammad H, Kulesskaya N, Deshpande P, Marchisella F, Mysore R, Hollos P, Michelsen KA, Mågard M, Rauvala H, James P, Coffey ET. JNK1 controls dendritic field size in L2/3 and L5 of the motor cortex, constrains soma size, and influences fine motor coordination. Front Cell Neurosci. 2014 Sep 12;8:272.

Koskinen A, Lukkarinen H, Laine J, Ahotupa M, Kääpä P, Soukka H. Delay in rat lung alveolarization after the combined exposure of maternal hyperglycemia and postnatal hyperoxia. Pediatr Pulmonol. 2014 Feb;49(2):179-88.

Kyläniemi MK, Kaukonen R, Myllyviita J, Rasool O, Lahesmaa R. The regulation and role of c-FLIP in human Th cell differentiation. PLoS One. 2014 Jul 14;9(7):e102022.

Mai A, Muharram G, Barrow-McGee R, Baghirov H, Rantala J, Kermorgant S, Ivaska J. Distinct c-Met activation mechanisms induce cell rounding or invasion through pathways involving integrins, RhoA and HIP1. J Cell Sci. 2014 May 1;127(Pt 9):1938-52.

Muharram G, Sahgal P, Korpela T, De Franceschi N, Kaukonen R, Clark K, Tulasne D, Carpén O, Ivaska J. Tensin-4-dependent MET stabilization is essential for survival and proliferation in carcinoma cells. Dev Cell. 2014 May 27;29(4):421-36. Erratum in: Dev Cell. 2014 Jun 9:29(5):629-30.

Mäkelä JA, Toppari J, Rivero-Müller A, Ventelä S. Reconstruction of mouse testicular cellular microenvironments in long-term seminiferous tubule culture. PLoS One. 2014 Mar 11;9(3):e90088.

Mäki-Jouppila JH, Laine LJ, Rehnberg J, Narvi E, Tiikkainen P, Hukasova E, Halonen P, Lindqvist A, Kallio L, Poso A, Kallio MJ. Centmitor-1, a novel acridinyl-acetohydrazide, possesses similar molecular interaction field and antimitotic cellular phenotype as rigosertib, on 01910.Na. Mol Cancer Ther. 2014 May;13(5):1054-66.

Paatero I, Seagroves TN, Vaparanta K, Han W, Jones FE, Johnson RS, Elenius K. Hypoxia-inducible factor-1α induces ErbB4 signaling in the differentiating mammary gland. J Biol Chem. 2014 Aug 8;289(32):22459-69.

Paul P, Rajendran SK, Peuhu E, Alshatwi AA, Akbarsha MA, Hietanen S, Eriksson JE. Novel action modality of the diterpenoid anisomelic acid causes depletion of E6 and E7 viral oncoproteins in HPV-transformed cervical carcinoma cells. Biochem Pharmacol. 2014 May 15;89(2):171-84.

Rotgers E, Rivero-Müller A, Nurmio M, Parvinen M, Guillou F, Huhtaniemi I, Kotaja N, Bourguiba-Hachemi S, Toppari J. Retinoblastoma protein (RB) interacts with E2F3 to control terminal differentiation of Sertoli cells. Cell Death Dis. 2014 Jun 5;5:e1274.

Siljamäki E, Raiko L, Toriseva M, Nissinen L, Näreoja T, Peltonen J, Kähäri VM, Peltonen. p38δ mitogen-activated protein kinase regulates the expression of tight junction protein ZO-1 in differentiating human epidermal keratinocytes.  Arch Dermatol Res. 2014 Mar;306(2):131-41.

Sipilä K, Haag S, Denessiouk K, Käpylä J, Peters EC, Denesyuk A, Hansen U, Konttinen Y, Johnson MS, Holmdahl R, Heino J. Citrullination of collagen II affects integrin-mediated cell adhesion in a receptor-specific manner. FASEB J. 2014 Aug;28(8):3758-68.

Sjöqvist M, Antfolk D, Ferraris S, Rraklli V, Haga C, Antila C, Mutvei A, Imanishi SY, Holmberg J, Jin S, Eriksson JE, Lendahl U, Sahlgren C. PKCζ regulates Notch receptor routing and activity in a Notch signaling-dependent manner. Cell Res. 2014 Apr;24(4):433-50.

Trehan A, Rotgers E, Coffey ET, Huhtaniemi I, Rivero-Müller A. CANDLES, an assay for monitoring GPCR induced cAMP generation in cell cultures. Cell Commun Signal. 2014 Nov 4;12(1):70.

Virtanen SS, Kukkonen-Macchi A, Vainio M, Elima K, Härkönen PL, Jalkanen S, Yegutkin GG. Adenosine inhibits tumor cell invasion via receptor-independent mechanisms. Mol Cancer Res. 2014 Dec;12(12):1863-74.

Winsel S, Mäki-Jouppila J, Tambe M, Aure MR, Pruikkonen S, Salmela AL, Halonen T, Leivonen SK, Kallio L, Børresen-Dale AL, Kallio M1. Excess of miRNA-378a-5p perturbs mitotic fidelity and correlates with breast cancer tumourigenesis in vivo. Br J Cancer. 2014 Nov 25;111(11):2142-51.

Yegutkin GG, Auvinen K, Karikoski M, Rantakari P, Gerke H, Elima K, Maksimow M, Quintero IB, Vihko P, Salmi M, Jalkanen S. Consequences of the lack of CD73 and prostatic acid phosphatase in the lymphoid organs. Mediators Inflamm. 2014;2014:485743.