Protein Chemistry & Structure

Protein Chemistry & Structure

We use structural biochemistry methods to understand the structure-function relationship of biomacromolecules. Our main technique is X-ray crystallography with long expertise on all steps of protein structure determination:

  • Protein purification and characterization
  • Crystallisation
  • Data collection and processing
  • Phasing
  • Model building, refinement and analysis

Our studies are complemented with computational and experimental techniques, such as homology modelling, docking, small-angle X-ray scattering, and biophysical techniques (calorimetry, thermal shift assay, light scattering, thermophoresis). A major application of our studies is in the design of new drugs and we are part of the Drug Development and Diagnostics  common research profiling area of UTU and ÅAU.

The Facility is able to undertake projects from Academic groups and companies, either as a collaborative effort or as a service.