Instruments at the Screening Unit

1. High-Throughput/High-Content System

  •  Pathway855 High-Content Analyser
    • for live cell/small model organism HCA with on-stage pipetting (Beckton Dickinson)
  • Integrated live-cell incubator (capacity 42 plates, Thermo Scientific Cytomat 2C-LIN)
  • Integrated ambient Twister stacks (capacity 120 plates/tip racks x 2)
  • Cooled stack (capacity 40 plates)
  • Cooled plate holder
  • Polarstar Plate reader (BMG)
  • Barcode Reader
  • Biomek NXP96/384 pipetting robot (Beckman Coulter)
  • Cell Plate Washer option (Thermo Fisher Wellwash Versa)
  • Reagent Dispenser option (Thermo Fisher Multidrop)
  • 3-gas mixer

2. High-Content Screening system

Operetta confocal HCS instrument (Perkin Elmer)

3. Live-cell imaging and analysis platform

Incucyte (Essen Bioscience)

4. Off-line instruments

  • Acoustic non-contact Dispenser (EDC Biosystems)
  • Additional Reagent Dispenser (Thermo Fisher Multidrop)
  • Plate Reader (Perkin Elmer Envision)
  • Cell Incubators (Hera)
  • Scanning Confocal Microscope (Biorad Radiance 7 line 4 detectors)
  • Multi-point Wide-Field Fast Imaging Microscope (Custom)
  • Plate Washer (Tecan)
  • Spinning-Disk Confocal Microscope (3i)

5. Image Analysis

  • Image analysis suite (3 workstations) linked to image data server with multiple analysis software packages
  • Image data server 1 (32TB)
  • Image data server 2 (24TB)
  • Image data server 3 (30TB)