Publications

Maria Georgiadou, Johanna Lilja, Guillaume Jacquemet, Camilo Guzmán, Maria Rafaeva, Charlotte Alibert, Yan Yan, Pranshu Sahgal, Martina Lerche, Jean‑Baptiste Manneville, Tomi P. Mäkelä and Johanna Ivaska. AMPK negatively regulates tensin-dependent integrin activity. Journal of Cell Biology. Published online 13th March 2017. Pubmed

Emilia Peuhu, Riina Kaukonen, Martina Lerche, Markku Saari, Camilo Guzmán, Pia Rantakari, Nicola De Franceschi, Anni Wärri, Maria Georgiadou, Guillaume Jacquemet, Elina Mattila, Reetta Virtakoivu, Yuming Liu, Youmna Attieh, Kathleen A Silva, Timo Betz, John P Sundberg, Marko Salmi, Marie‐Ange Deugnier, Kevin W Eliceiri, Johanna Ivaska. SHARPIN regulates collagen architecture and ductal outgrowth in the developing mouse mammary gland. The EMBO Journal (2017) 36, 165-182. Pubmed

Johanna Lilja, Thomas Zacharchenko, Maria Georgiadou, Guillaume Jacquemet, Nicola De Franceschi, Emilia Peuhu, Hellyeh Hamidi, Jeroen Pouwels, Victoria Martens, Fatemeh Hassani Nia, Malte Beifuss, Tobias Boeckers, Hans-Juergen Kreienkamp, Igor L. Barsukov & Johanna Ivaska. SHANK proteins limit integrin activation by directly interacting with Rap1 and R-Ras. Nature Cell Biology (2017). Published online 06 March 2017. Link

Fatemeh Seyednasrollah, Mehrad Mahmoudian, Liisa Rautakorpi, Outi Hirvonen, Tarja Laitinen, Sirkku Jyrkkiö, Laura L. Elo. How Reliable are Trial-based Prognostic Models in Real-world Patients with Metastatic Castration-resistant Prostate Cancer? European Urology, Feb 8, 2017. Pubmed

Wang J, Okkeri J, Pavic K, Wang Z, Kauko O, Halonen T, Sarek G, Ojala PM, Rao Z, Xu W, Westermarck J. Oncoprotein CIP2A is stabilized via interaction with tumor suppressor PP2A/B56. EMBO Rep. 2017 Feb 7. [Epub ahead of print]. Pubmed

Suomi T, Elo LL. Methods. Mol Biol., 2017. Accurate Detection of Differential Expression and Splicing Using Low-Level Features. Link

Mohammad H et al. Mol Psychiatry, 2016. JNK1 controls adult hippocampal neurogenesis and imposes cell-autonomous control of anxiety behaviour from the neurogenic niche.  Link

Guillaume J et al. Nature Communications, 2016. L-type calcium channels regulate filopodia stability and cancer cell invasion downstream of integrin signalling. Link

Laajala TD et al. Sci Rep., 2016. Longitudinal modeling of ultrasensitive and traditional prostate-specific antigen and prediction of biochemical recurrence after radical prostatectomy. Link

Mahmoudian M. et al. F1000Research, 2016. A predictive model of overall survival in patients with metastatic castration-resistant prostate cancer. Link

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News

29.03.2017 15:19

Scientific Discovery Opens New Possibilities for Cancer and Fibrosis Treatment

Researchers from the Turku Centre for Biotechnology (BTK) in Finland have discovered that a...


14.03.2017 10:20

The researchers from Turku Centre for Biotechnology discovered an unexpected link between cancer and autism

The novel discovery impinges upon the protein called SHANK which has been intensively studied in...


10.02.2017 09:57

Johanna Ivaskalle Orionilta 100-vuotisjuhlavuoden apuraha

Akatemiaprofessori Johanna Ivaska Turun yliopistosta saa Orionin Tutkimussäätiöltä 100 000 euron...


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