Turku Centre for Biotechnology is a joint department of the University of Turku and Åbo Akademi University, providing high-end technologies and expertise to academic and industrial researchers. These services benefit from the internationally competitive, excellent research carried out by CBT investigators. Our researchers discover molecular events underlying biological function and identify how this information can be used to improve life quality.
Maria Georgiadou, Johanna Lilja, Guillaume Jacquemet, Camilo Guzmán, Maria Rafaeva, Charlotte Alibert, Yan Yan, Pranshu Sahgal, Martina Lerche, Jean‑Baptiste Manneville, Tomi P. Mäkelä and Johanna Ivaska. AMPK negatively regulates tensin-dependent integrin activity. Journal of Cell Biology. Published online 13th March 2017. Pubmed
Emilia Peuhu, Riina Kaukonen, Martina Lerche, Markku Saari, Camilo Guzmán, Pia Rantakari, Nicola De Franceschi, Anni Wärri, Maria Georgiadou, Guillaume Jacquemet, Elina Mattila, Reetta Virtakoivu, Yuming Liu, Youmna Attieh, Kathleen A Silva, Timo Betz, John P Sundberg, Marko Salmi, Marie‐Ange Deugnier, Kevin W Eliceiri, Johanna Ivaska. SHARPIN regulates collagen architecture and ductal outgrowth in the developing mouse mammary gland. The EMBO Journal (2017) 36, 165-182. Pubmed
Johanna Lilja, Thomas Zacharchenko, Maria Georgiadou, Guillaume Jacquemet, Nicola De Franceschi, Emilia Peuhu, Hellyeh Hamidi, Jeroen Pouwels, Victoria Martens, Fatemeh Hassani Nia, Malte Beifuss, Tobias Boeckers, Hans-Juergen Kreienkamp, Igor L. Barsukov & Johanna Ivaska. SHANK proteins limit integrin activation by directly interacting with Rap1 and R-Ras. Nature Cell Biology (2017). Published online 06 March 2017. Link
Fatemeh Seyednasrollah, Mehrad Mahmoudian, Liisa Rautakorpi, Outi Hirvonen, Tarja Laitinen, Sirkku Jyrkkiö, Laura L. Elo. How Reliable are Trial-based Prognostic Models in Real-world Patients with Metastatic Castration-resistant Prostate Cancer? European Urology, Feb 8, 2017. Pubmed
Wang J, Okkeri J, Pavic K, Wang Z, Kauko O, Halonen T, Sarek G, Ojala PM, Rao Z, Xu W, Westermarck J. Oncoprotein CIP2A is stabilized via interaction with tumor suppressor PP2A/B56. EMBO Rep. 2017 Feb 7. [Epub ahead of print]. Pubmed
Suomi T, Elo LL. Methods. Mol Biol., 2017. Accurate Detection of Differential Expression and Splicing Using Low-Level Features. Link
Mohammad H et al. Mol Psychiatry, 2016. JNK1 controls adult hippocampal neurogenesis and imposes cell-autonomous control of anxiety behaviour from the neurogenic niche. Link
Guillaume J et al. Nature Communications, 2016. L-type calcium channels regulate filopodia stability and cancer cell invasion downstream of integrin signalling. Link
Laajala TD et al. Sci Rep., 2016. Longitudinal modeling of ultrasensitive and traditional prostate-specific antigen and prediction of biochemical recurrence after radical prostatectomy. Link
Mahmoudian M. et al. F1000Research, 2016. A predictive model of overall survival in patients with metastatic castration-resistant prostate cancer. Link
We offer state-of-the-art technology platforms and expertise in the areas of genomics, proteomics and imaging as well as viral vectors, x-ray crystallography and bioinformatics. These core facilities operate within the Biocenter Finland national infrastructure network providing services for local as well as national and international scientists.
Drop by anytime to learn how CBT can advance your research in ways previously unforeseen!
Researchers from the Turku Centre for Biotechnology (BTK) in Finland have discovered that a...
The novel discovery impinges upon the protein called SHANK which has been intensively studied in...
Akatemiaprofessori Johanna Ivaska Turun yliopistosta saa Orionin Tutkimussäätiöltä 100 000 euron...
Tuesday, April 04 2017 at 12:00 Impact of diet on neurocognitive function
Wednesday, April 05 2017 at 11:15 An overview of primary immunodeficiency
Thursday, April 06 2017 at 12:00 γδ T-cells: An immune cell population at the cross-road of innate and adaptive immunity